Pronađeno 91 radova, za izraz:
"PROJEKT: (Dizajn, sinteza i evaluacija novih protuotrova kod trovanja živčanim bojnim otrovima i pesticidima (CHOLINESTERASE) (IP-2013-11-4307))"
DODAJ/IZMIJENI OPERATORE PRETRAŽIVANJA
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26.Zorbaz, Tamara; Malinak, David; Maraković, Nikola; Maček Hrvat, Nikolina; Zandona, Antonio; Novotny, Michal; Skarka, Adam; Andrys, Rudolf; Benkova, Marketa; Soukup, Ondrej et al.Pyridinium oximes with ortho-positioned chlorine moiety exhibit improved physico- chemical properties and efficient reactivation of human acetylcholinesterase inhibited by several nerve agents // Journal of Medicinal Chemistry, 61 (2018), 23; 10753-10766 doi:10.1021/acs.jmedchem.8b01398 (međunarodna recenzija, članak, znanstveni)
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27.Bosak, Anita; Ramić, Alma; Šmidlehner, Tamara; Hrenar, Tomica; Primožič, Ines; Kovarik, ZrinkaDesign and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold // PLoS One, - (2018), e0205193, 11 doi:10.1371/journal.pone.0205193 (međunarodna recenzija, članak, znanstveni)
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28.Kovarik, Zrinka; Katalinić, Maja; Maček Hrvat, Nikolina; Šinko, Goran; Zorbaz, Tamara; Bosak, AnitaEnhancement in pyridinium oxime-assisted reactivation of tabun-inhibited acetylcholinesterase achieved by active site mutations // Programme and Abstract Book, Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Republika Češka, 2018 / Korábečný, Jan ; Soukup, Ondrej (ur.).
Hradec Kralove: University of Defence, Faculty of Military Health Sciences, Czech Republic, 2018. str. 35-35 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
29.Zorbaz, Tamara; Maraković, Nikola; Musilek, Kamil; Kovarik, ZrinkaChlorinated pyridinium oximes are potent reactivators of acetylcholinesterase inhibited by nerve agents // Programme and Abstract Book, Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Republika Češka, 2018 / Korábečný, Jan ; Soukup, Ondrej (ur.).
Hradec Kralove: University of Defence, Faculty of Military Health Sciences, Czech Republic, 2018. str. 78-78 (poster, međunarodna recenzija, sažetak, znanstveni) -
30.Zorbaz, Tamara; Mišetić, Petra; Zandona, Antonio; Braiki, Anissa; Maček Hrvat, Nikolina; Katalinić, Maja; Gabelica Marković, Vesna; Jean, Ludovic; Renard, Pierre-Yves; Kovarik, ZrinkaPotent lipophilic reactivators of phosphorylated cholinesterases are not cytotoxic and are metabolically stable // FEBS3+ Conference: From Molecules to Living Systems : Final Programme & Book of Abstracts / Szüts, Dávis ; Buday, László (ur.).
Veszprém: OOK-Press, 2018. str. 89-89 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
31.Bosak, Anita; Opsenica, Dejan M.; Šinko, Goran; Zlatar, Matija; Kovarik, Zrinka4-aminoquinilines as reversible inhibitors of human cholinesterase activity // Programme and Abstract Book, Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Republika Češka, 2018 / Korábečný, Jan ; Soukup, Ondrej (ur.).
Hradec Kralove: University of Defence, Faculty of Military Health Sciences, Czech Republic, 2018. str. 73-73 (poster, međunarodna recenzija, sažetak, znanstveni) -
32.Šinko, GoranAssessment of scoring functions for ache-ligand interactions // Programme and Abstract Book, Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases / Korabečny, Jan ; Soukup, Ondrej (ur.).
Hradec Kralove, 2018. str. 36-36 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
33.Zandona, Antonio; Primožič, Ines; Katalinić, Maja; Kovarik, ZrinkaIn vitro evaluation of quinuclidinium oximes as reactivators of organophosphorus compounds inhibited human cholinesterases // Programme and Abstract Book in Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases / Korábečný, Jan ; Soukup, Ondřej (ur.).
Hradec Kralove, 2018. str. 85-85 (poster, međunarodna recenzija, sažetak, znanstveni) -
34.Maček Hrvat, Nikolina; Kalisiak, Jarosław; Zandona, Antonio; Šinko, Goran; Radić, Zoran; Sharpless, K. Barry; Taylor, Palmer; Kovarik ZrinkaPhenyltetrahydroisoquinoline-based triazole compounds are high- affinity potential reactivators of nerve agent-inhibited human acetylcholinesterase // Programme and Abstract Book, Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Republika Češka, 2018 / Korábečný, Jan ; Soukup, Ondrej (ur.).
Hradec Kralove: University of Defence, Faculty of Military Health Sciences, Czech Republic, 2018. str. 76-76 (poster, međunarodna recenzija, sažetak, znanstveni) -
35.Sit, Rakesh K.; Kovarik, Zrinka; Maček Hrvat, Nikolina; Žunec, Suzana; Green, Carol; Fokin, Valery V.; Sharpless, K. Barry; Radić, Zoran; Taylor, PalmerPharmacology, pharmacokinetics and tissue disposition of zwitterionic hydroxyiminoacetamido alkylamines as reactivating antidotes for organophosphate exposure // The Journal of pharmacology and experimental therapeutics, 367 (2018), 2; 363-372 doi:10.1124/jpet.118.249383 (međunarodna recenzija, članak, znanstveni)
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36.Katalinić, Maja; Šinko, Goran; Maček Hrvat, Nikolina; Zorbaz, Tamara; Bosak, Anita; Kovarik, ZrinkaOxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations // Toxicology, 406-407 (2018), 104-113 doi:10.1016/j.tox.2018.05.008 (međunarodna recenzija, članak, znanstveni)
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37.Bosak, Anita; Knežević, Anamarija; Zlatić, Katarina; Kerep, Robert; Kovarik, ZrinkaCarbamate derivatives of short-acting bronchodilator albuterol inhibits human acetylcholinesterase and butyrylcholinesterase // Book of Abstracts of the 10th Congress of Toxicology in Developing Countries and 12th Congress of the serbian Society of Toxicology
Beograd, Srbija, 2018. str. 114-114 (poster, međunarodna recenzija, sažetak, znanstveni) -
38.Zorbaz, Tamara; Braïki, Anissa; Maraković, Nikola; Renou, Julien; de la Mora, Eugenio; Maček Hrvat, Nikolina; Katalinić, Maja; Silman, Israel; Sussman, Joel L; Mercey, Guillaume et al.Potent 3-hydroxy-2-pyridine aldoxime reactivators of organophosphate-inhibited cholinesterases with predicted blood-brain barrier penetration // Chemistry : a European journal, 24 (2018), 38; 9675-9691 doi:10.1002/chem.201801394 (međunarodna recenzija, članak, znanstveni)
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39.Maček Hrvat, Nikolina; Zorbaz, Tamara; Šinko, Goran; Kovarik, ZrinkaThe estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation // Toxicology letters, 293 (2018), 222-228 doi:10.1016/j.toxlet.2017.11.022 (međunarodna recenzija, članak, znanstveni)
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40.Zorbaz, TamaraMozak "pod utjecajem" // Priroda, 1058 (2017), 17/18; 11-15 (domaća recenzija, članak, stručni)
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41.Zorbaz, Tamara; Katalinić, Maja; Zandona, Antonio; Braiki, Anissa; Jean, Ludovic; Renard, Pierre-Yves; Kovarik, ZrinkaNovel centrally active antidote for intoxication by sarin and VX nerve agents // Knjiga Sažetaka Mini simpozija Sekcije za medicinsku i farmaceutsku kemiju
Zagreb, Hrvatska, 2017. str. 4-4 (predavanje, domaća recenzija, sažetak, znanstveni) -
42.Maček Hrvat, Nikolina; Radić, Zoran; Taylor, Palmer; Kovarik, ZrinkaOxime-assisted detoxification of nerve agents by a human AChE mutant // Knjiga Sažetaka Mini simpozija Sekcije za medicinsku i farmaceutsku kemiju. Zagreb, Hrvatska, 2017.
Zagreb, Hrvatska, 2017. str. 3-3 (predavanje, domaća recenzija, sažetak, znanstveni) -
43.Kovarik, Zrinka; Maček Hrvat, Nikolina; Zorbaz, Tamara; Kalisiak, Jaroslav; Sharpless, K. Barry; Radić, Zoran; Taylor, PalmerAcetylcholinesterase and novel oxime reactivators in counteracting organophosphate exposure // The FEBS Journal, Volume 284, Issue S1, Supplement:42nd FEBS Congress, From Molecules to Cells and Back, Jerusalem, Israel, September 10‐14, 2017
Jeruzalem, Izrael, 2017. str. 390-390 (poster, međunarodna recenzija, sažetak, znanstveni) -
44.Zorbaz, Tamara; Katalinić, Maja; Zandona, Antonio; Braiki, Anissa; Jean, Ludovic; Renard, Pierre Yves; Kovarik, ZrinkaNovel centrally active antidote for intoxication by sarin and VX nerve agents // The FEBS Journal, Volume 284, Issue S1, Supplement:42nd FEBS Congress, From Molecules to Cells and Back, Jerusalem, Israel, September 10‐14, 2017
Jeruzalem, Izrael, 2017. str. 242-242 doi:10.1111/febs.14174 (poster, međunarodna recenzija, sažetak, znanstveni) -
45.Bosak, Anita; Bavec, Aljoša; Goličnik, Marko; Šinko, Goran; Kovarik, ZrinkaKinetic evaluation of PON1 interactions with pharmacologically active carbamates // 12th Meeting of the Slovenian Biochemical Society with International Participation, Book of Abstracts, 20-23 September 2017, Bled, Slovenia / Goričar, Katja ; Hudler, Petra (ur.).
Ljubljana: Slovenian Biochemical Society, 2017. str. 109-109 (poster, međunarodna recenzija, sažetak, ostalo) -
46.Zandona, Antonio; Zorbaz, Tamara; Kovarik, Zrinka; Katalinić, MajaCytotoxicity of oximes tested as antidotes in organophosphorus compound poisoning // 12th Meeting of the Slovenian Biochemical Society with International Participation, Book of Abstracts, 20-23 September 2017, Bled, Slovenia / Goričar, Katja ; Hudler, Petra (ur.).
Ljubljana: Slovenian Biochemical Society, 2017. str. 82-82 (poster, sažetak, ostalo) -
47.Maraković, Nikola; Knežević, Anamarija; Vinković, Vladimir; Kovarik, Zrinka; Šinko, GoranReactivation efficacy of new chiral N-substituted 2-hydroxyiminoacetamide reactivators of phosphylated cholinesterases // 12th Meeting of the Slovenian Biochemical Society with International Participation : Book of Abstracts / Goričar, Katja ; Hudler, Petra (ur.).
Ljubljana: Slovenian Biochemical Society, 2017. str. 106-106 (poster, međunarodna recenzija, sažetak, znanstveni) -
48.Katalinić, Maja; Zandona, Antonio; Ramić, Alma; Zorbaz, Tamara; Primožič, Ines; Kovarik, ZrinkaNew cinchona oximes evaluated as reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by organophosphorus compounds // Molecules, 22 (2017), 1234, 13 doi:10.3390/molecules22071234 (međunarodna recenzija, članak, znanstveni)
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49.Kovarik, Zrinka; Maček-Hrvat, Nikolina; Zorbaz, TamaraMedical chemical defence against chemical nerve agent threats // Book of Abstract of 10th Joint Meeting on Medicinal Chemistry, Dubrovnik (Srebreno) / Basarić, Nikola ; Namjesnik, Danijel ; Perković, Ivana ; Stepanić, Višnja (ur.).
Zagreb: Hrvatsko kemijsko društvo, 2017. str. 143-143 (poster, međunarodna recenzija, sažetak, znanstveni) -
50.Bosak, Anita; Kovarik, ZrinkaCan the BCHE polymorphism affect the inhibition potency of carbamylating and reversible inhibitors from everyday life? // Book of Abstract of 10th Joint Meeting on Medicinal Chemistry, Dubrovnik (Srebreno) / Basarić, Nikola ; Namjesnik, Danijel ; Perković, Ivana ; Stepanić, Višnja (ur.).
Zagreb: Hrvatsko kemijsko društvo, 2017. (poster, međunarodna recenzija, sažetak, znanstveni)
