Pronađeno 88 radova, za izraz:
"PROJEKT: (Mehanizam djelovanja kolesterola u nastanku Alzheimerove bolesti (MZOS-098-0982522-2525))"
DODAJ/IZMIJENI OPERATORE PRETRAŽIVANJA
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1.Dražić, Tonko; Vazdar, Katarina; Vazdar, Mario; Đaković, Marijana; Mikecin, Ana-Matea; Kralj, Marijeta; Malnar, Martina; Hećimović, Silva; Habuš, IvanSynthesis of new 2-aminoimidazolones with antiproliferative activity via base promoted amino-β-lactam rearrangement // Tetrahedron, 71 (2015), 49; 9202-9215 doi:10.1016/j.tet.2015.10.048 (međunarodna recenzija, članak, znanstveni)
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2.Dražić, Tonko; Molčanov, Krešimir; Sachdev, Vinay; Malnar, Martina; Hećimović, Silva; Patankar, Jay V.; Obrowsky, Sascha; Levak-Frank, Sanja; Habuš, Ivan; Kratky, DagmarNovel amino-β-lactam derivatives as potent cholesterol absorption inhibitors // European journal of medicinal chemistry, 87 (2014), 722-734 doi:10.1016/j.ejmech.2014.10.014 (međunarodna recenzija, članak, znanstveni)
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3.Cermak, Stjepko; Causevic, Mirsada; Kuhn, Peer-Hendrik; Gunnersen, Jenny; Hutter-Paier, Birgit; Windisch, Manfred; Lichtenthaler, Stefan; Hecimovic, SilvaAltered metabolism of BACE1 substrates seizure protein 6 and seizure 6-like protein 1 in Niemann-Pick type C disease // Alzheimer's & Dementia / Schneider, Lon S. (ur.).
New York (NY): Elsevier, 2014. str. P877-P878 (poster, međunarodna recenzija, sažetak, znanstveni) -
4.Jović, TanjaIzolacija i karakterizacija lizosoma u stanicama CHOwt i CHO NPC1-null, 2014., diplomski rad, diplomski, Farmaceutsko-biokemijski fakultet, Zagreb
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5.Dominko, KristinaMeđudjelovanje kolesterola i antioksidativnog sustava, 2014., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Zagreb
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6.Silvestrić, AnaThe analysis of presenilin cellular localization in Niemann-Pick type C cells, 2014., diplomski rad, diplomski, Facoltà di Medicina e Chirurgia, Trieste
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7.Košiček, Marko; Wunderlich, Patrick; Walter, Jochen; Hećimović, SilvaGGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells // Biochemical and biophysical research communications, 450 (2014), 1; 160-165 doi:10.1016/j.bbrc.2014.05.083 (međunarodna recenzija, članak, znanstveni)
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8.Katušić Hećimović, Silva; Malnar, Martina; Košiček, MarkoNiemann-Pick type C disease – a model to study the role of cholesterol in the pathogenesis of Alzheimer's disease // The 19th European Study Group on Lysosomal Diseases (ESGLD
Graz, Austrija, 2013. (poster, međunarodna recenzija, neobjavljeni rad, znanstveni) -
9.Katušić Hećimović, SilvaThe Role of APP in Cholesterol Metabolism: A link between Niemann-Pick type C Disease and Alzheimer's Disease // Workshop MSLife: High Performance Mass Spectrometry: Integration new tools and methods with Applications in Life Sciences
Konstanz, Njemačka, 2013. (pozvano predavanje, neobjavljeni rad, znanstveni) -
10.Košiček, MarkoUtjecaj lipida na patogenezu Alzheimerove bolesti - od molekularnog mehanizma do biomarkera bolesti, 2013., doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb
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11.Malnar, Martina; Košiček, Marko; Mitterreiter, Stefan; Lichtenthaler, Stefan F.; Hećimović, Silva.Cholesterol accumulation in Niemann-Pick type C cells favors APP processing by β-secretase and causes altered endocytic trafficking of BACE1 // Kloster Seeon meeting on BACE proteases in health and disease
Seeon-Seebruck, Njemačka, 2013. (poster, neobjavljeni rad, znanstveni) -
12.Hećimović, Silva; Košiček, Marko; Malnar, MartinaCholesterol Levels Modulate Endosomal Localization of BACE1 // AD/PD 2013 The 11th International Conference On Alzheimer's & Parkinson's Disease
Firenca, Italija, 2013. (poster, sažetak, znanstveni) -
13.von Arnim, Christine; von Einem, Bjorn; Weber, Petra; Wagner, Michael; Malnar, Martina; Košiček, Marko; Hećimović, Silva; Schneckenburger, HerbertProtein Proximity of APP and BACE1 and Membrane Stiffness Is Altered in Different Membranes in Niemann-Pick Type C Disease Cells // AD/PD 2013 The 11th International Conference On Alzheimer's & Parkinson's Disease
Firenca, Italija, 2013. (poster, sažetak, znanstveni) -
14.Štefulj, Jasminka; Perić, Maja; Malnar, Martina; Košiček, Marko; Schweinzer, Cornelia; Živković, Jelena; Scholler, Monika; Panzenboeck, Ute; Hećimović, SilvaPharmacological activation of LXRs decreases amyloid-β levels in Niemann-Pick type C model cells // Current pharmaceutical biotechnology, 14 (2013), 6; 582-593 (međunarodna recenzija, članak, znanstveni)
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15.Malnar, Martina; Košiček, Marko; Tahirović, Sabina; Katušić Hećimović SilvaCholesterol levels modulate trafficking of APP and BACE1 in Niemann-Pick type C cells // Gordon Research Conference: Lysosomal Diseases
Barga, Italija, 2013. (poster, neobjavljeni rad, znanstveni) -
16.Malnar, Martina; Košiček, Marko; Tahirović, Sabina; Katušić Hećimović, SilvaCholesterol levels modulate trafficking of APP and BACE1 in Niemann-Pick type C cells // Gordon Research Seminar: Lysosomal diseases
Barga, Italija, 2013. (pozvano predavanje, neobjavljeni rad, znanstveni) -
17.Katušić Hećimović, SilvaThe link between NP-C and Alzheimer’s disease // Pharmaceuticals Ltd. Joint International Advisory Board Meeting on Niemann-Pick Type C
Zürich, Švicarska, 2012. (pozvano predavanje, međunarodna recenzija, neobjavljeni rad, znanstveni) -
18.Katušić Hećimović, SilvaThe molecular links between lysosomal storage diseases and Alzheimer’s disease // Workshop New Developments of Lysosomal storage disease diagnostics & therapeutics: LSD Protein – aggregation & interactions
Konstanz, Njemačka, 2012. (pozvano predavanje, neobjavljeni rad, znanstveni) -
19.von Einem, Bjorn; Weber, Petra; Wagner, Michael; Malnar, Martina; Košiček, Marko; Hećimović, Silva; von Arnim, Christine; Schneckenburger, HerbertCholesterol dependent energy transfer between fluorescent proteins - insights into protein proximity of APP and BACE1 in different membranes in Niemann-Pick type C disease cells // International journal of molecular sciences, 13 (2012), 12; 15801-15812 doi:10.3390/ijms131215801 (međunarodna recenzija, članak, znanstveni)
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20.Košiček, Marko; Zetterberg, Henrik; Andreasen, Niels; Peter-Katalinić, Jasna; Hećimović, SilvaElevated cerebrospinal fluid sphingomyelin levels in prodromal Alzheimer’s disease // Neuroscience letters, 516 (2012), 2; 302-305 doi:10.1016/j.neulet.2012.04.019 (međunarodna recenzija, članak, znanstveni)
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21.Mattsson, Niklas; Olsson, Maria; Gustavsson, Mikael K.; Košiček, Marko; Malnar, Martina; Månsson, Jan-Eric; Blomqvist, Maria; Gobom, Johan; Andreasson, Ulf; Brinkmalm, Gunnar et al.Amyloid-β metabolism in Niemann-Pick C disease models and patients // Metabolic brain disease, 27 (2012), 4; 573-585 doi:10.1007/s11011-012-9332-8 (međunarodna recenzija, članak, znanstveni)
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22.Malnar, MartinaMehanizam djelovanja kolesterola na cijepanje i transport proteina APP, 2012., doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb
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23.Perić, MajaUčinci sintetskih liganada jetrenih receptora X (LXR) na metabolizam proteina prekursora amiloida u staničnom modelu bolesti Niemann Pick tipa C1, 2012., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Zagreb
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24.Malnar, Martina; Košiček, Marko; Lisica, Ana; Posavec, Melanija; Krolo, Ana; Njavro, Jasenka; Omerbašić, Damir; Tahirović, Sabina; Hećimović, SilvaCholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells // Biochimica et biophysica acta-molecular basis of disease, 1822 (2012), 8; 1270-1283 doi:10.1016/j.bbadis.2012.04.002 (međunarodna recenzija, članak, znanstveni)
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25.Malnar, Martina; Košiček, Marko; Bene, Raphael; Petek Tarnik, Iva; Pavelin, Sanda; Babić, Ivana; Brajenović-Milić, Bojana; Hećimović, Hrvoje; Titlić, Marina; Trkanjec, Zlatko et al.Use of cerebrospinal fluid biomarker analysis and apolipoprotein E genotyping for improving Alzheimer’s disease diagnosis in a non-specialized setting // Acta neurobiologiae experimentalis, 72 (2012), 3; 264-271 (međunarodna recenzija, članak, znanstveni)
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26.Katušić Hećimović, SilvaMolecular mechanism(s) of increased Aß upon cholesterol accumulation in Niemann-Pick type C disease // German Center for Neurodegenerative Diseases Munich - Seminar
München, Njemačka, 2011. (pozvano predavanje, neobjavljeni rad, znanstveni) -
27.Katušić Hećimović, SilvaLipid Profiling and its Role in the Pathogenesis of Alzheimer’s Disease // Workshop Bioaffinity – Mass Spectrometry: New Developments and Applications in Life Sciences
Konstanz, Njemačka, 2011. (pozvano predavanje, međunarodna recenzija, neobjavljeni rad, znanstveni) -
28.Katušić Hećimović, SilvaThe molecular mechanism(s) of increased amyloid-beta in Niemann Pick type C disease // Neurochem Laboratory Seminar, Sahlgren University Hospital
Göteborg, Švedska, 2011. (pozvano predavanje, neobjavljeni rad, znanstveni) -
29.Katušić Hećimović, SilvaEndocytic traffick jam in Niemann Pick type C disease – a cause of increased Alzheimer’s amyloid-β peptide formation // Gordon Research Conference – Lysosomal Diseases
Galveston (TX), Sjedinjene Američke Države, 2011. (pozvano predavanje, međunarodna recenzija, neobjavljeni rad, znanstveni) -
30.Hecimovic, SilvaEndocytic traffic jam in Niemann Pick type C disease - a cause of increased Alzheimer's amyloid-β formation // Gordon Research Conference - Lysosomal Diseases
Galveston (TX), Sjedinjene Američke Države, 2011. (pozvano predavanje, međunarodna recenzija, neobjavljeni rad, znanstveni) -
31.Njavro, JasenkaUtjecaj nakupljanja kolesterola u stanicama CHO NPC1-/- na smještaj proteina BACE1 u organelima endocitoznog puta, 2011., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Zagreb
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32.Štefulj, Jasminka; Malnar, Martina; Schweinzer, Cornelia; Košiček, Marko; Živković, Jelena; Panzenboeck, Ute; Hećimović Katušić, SilvaThe impacts of LXR ligand TO901317 on amyloid-β levels and cholesterol metabolism in Niemann-Pick type C (NPC) model cells // Alzheimer's and Dementia
New York (NY): Elsevier, 2011. str. e72-e72 doi:10.1016/j.jalz.2011.09.157 (poster, međunarodna recenzija, sažetak, znanstveni) -
33.Kosicek, Marko; Hecimovic, Silva; Kirsch, Stephan; Bene, Raphael; Trkanjec, Zlatko; Titlic, Marina; Bindila, Laura; Peter-Katalinic, JasnaSphingomyelin is elevated in cerebrospinal fluid of Alzheimer's disease patients // Alzheimer's and Dementia
New York (NY): Elsevier, 2011. str. 140-140 (poster, međunarodna recenzija, sažetak, znanstveni) -
34.Malnar, Martina; Lisica, Ana; Hećimović, SilvaLipid traffic jam in Niemann Pick type C disease causes altered endocytosis of APP // Alzheimer's and Dementia (Supplement)
New York (NY): Elsevier, 2011. str. 390-390 (poster, međunarodna recenzija, sažetak, znanstveni) -
35.Ringman, John M.; Gylys, Karen H.; Medina, Luis D.; Fox, Michelle; Kepe, Vladimir; Flores, Deborah L.; Apostolova, Liana G.; Barrio, Jorge R.; Small, Gary; Silverman, Daniel H. et al.Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation // Neuroscience letters, 487 (2011), 3; 287-292 doi:10.1016/j.neulet.2010.10.039 (međunarodna recenzija, članak, znanstveni)
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36.Kular, DoloresUtjecaj nakupljanja kolesterola na metabolizam proteina APLP1 i APLP2 u stanicama CHO NPC1-null, 2011., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Zagreb
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37.Živković, JelenaIstraživanje utjecaja TO901317 na procesiranje proteina APP u staničnom modelu bolesti Niemann Pick tipa C, 2011., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Zagreb
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38.Ringman, John M.; Gylys, Karen H.; Medina, Luis D.; Fox, Michelle; Kepe, Vladimir; Flores, Deborah L.; Apostolova, Liana G.; Barrio, Jorge R.; Small, Gary; Silverman, Daniel H. et al.Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation (Neurosci. Lett. 487 (2011) 287–292) // Neuroscience letters, 491 (2011), 2; 163-163 doi:10.1016/j.neulet.2011.01.021 (podatak o recenziji nije dostupan, ispravak, znanstveni)
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39.Katušić Hećimović, SilvaThe link between lipids and Alzheimer’s disease: a view from Niemann Pick type C disease // JSW Life Science Seminar
Grambach, Austrija, 2010. (pozvano predavanje, neobjavljeni rad, znanstveni) -
40.Košiček, Marko; Bindila, Laura; Peter-Katalinić, Jasna; Hećimović, SilvaCerebrospinal fluid lipidomics in Alzheimer's disease // FEBS/IUBMB workshop : Eukaryotic lipids : Treasure of Regulatory Information : Abstracts
Spétses, Grčka, 2010. (predavanje, međunarodna recenzija, sažetak, znanstveni) -
41.Košiček, Marko; Kirsch, Stefan; Bene, Raphael; Trkanjec, Zlatko; Titlić, Marina; Bindila, Laura; Peter-Katalinić, Jasna; Hećimović, SilvaNano-HPLC-MS analysis of phospholipids in cerebrospinal fluid of Alzheimer’s disease patients–a pilot study // Analytical and bioanalytical chemistry, 398 (2010), 7/8; 2929-2937 doi:10.1007/s00216-010-4273-8 (međunarodna recenzija, članak, znanstveni)
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42.Petek Tarnik, IvaUtjecaj polimorfizma ApoE i vaskularnih čimbenika rizika na nastanak Alzheimerove bolesti, 2010., doktorska disertacija, Prirodoslovno- matematički fakultet, Zagreb
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43.Košiček, Marko; Malnar, Martina; Goate, Alison; Katušić Hećimović, SilvaCholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts // Biochemical and biophysical research communications, 393 (2010), 3; 404-409 doi:10.1016/j.bbrc.2010.02.007 (međunarodna recenzija, članak, znanstveni)
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44.Malnar, Martina; Košiček, Marko; Mitterreiter, Stefan; Omerbašić, Damir; Lichtenthaler, Stefan F.; Goate, Alison; Hećimović Katušić, SilvaNiemann Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the β-secretase pathway // Biochimica et biophysica acta : molecular basis of disease, 1802 (2010), 7-8; 682-691 doi:10.1016/j.bbadis.2010.05.006 (međunarodna recenzija, članak, znanstveni)
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45.Košiček, Marko; Goate, Alison; Hećimović, SilvaThe role of lipid rafts on app processing and amyloid-beta formation // 3rd Summer Course on Mass Spectrometry in Biotechnology and Medicine 2009
Dubrovnik, Hrvatska, 2009. (poster, neobjavljeni rad, znanstveni) -
46.Malnar, Martina; Košiček, Marko; Hećimovicć, SilvaCholesterol accumulation upon NPC1 dysfunction alters APP expression at the cell surface leading to its increased processing through the β-secretase pathway // FEBS Advanced Course: Lipid signaling and disease 2009
Ortona, Italija, 2009. (poster, međunarodna recenzija, sažetak, znanstveni) -
47.Krolo, Ana; Lisica, Ana; Malnar, Martina; Košiček, Marko; Hećimović, SilvaAccumulation of cholesterol in Niemann Pick type C cells alters APP distribution within endosome compartments // FEBS Advanced Course: Lipid signaling and disease 2009
Ortona, Italija, 2009. (poster, međunarodna recenzija, sažetak, znanstveni) -
48.Posavec, Melanija; Krolo, Ana; Omerbašić, Damir; Lisica, Ana; Malnar, Martina; Košiček, Marko; Hećimović, SilvaCholesterol accumulation upon NPC1 dysfunction alters endosomal compartmentalization of β-amyloid precursor protein // EMBO Young Scientists Forum 2009
Zagreb, Hrvatska, 2009. (poster, međunarodna recenzija, sažetak, znanstveni) -
49.Krolo, AnaSmještaj proteina APP u organelima endocitoznog puta u stanicama CHO NPC1-null, 2009., diplomski rad, Prirodoslovno- matematički fakultet, Zagreb
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50.Lisica, AnaPrijenos proteina APP u organelima endocitoznog puta u stanicama CHO NPC1-null, 2009., diplomski rad, Prirodoslovno- matematički fakultet, Zagreb
