Pregled po projektu: Molekularni mehanizam neurodegeneracije u Niemann-Pickovoj bolesti tip C (neuroNiPiC) (MB: HRZZ-IP-2016-06-2799)
Pronađeno 21 radova
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1.Rastija, AnaIspitivanje uloge proteaze BACE1 u patogenezi rijetke nasljedne neurodegenerativne Niemann- Pickove bolesti tipa C, 2023., doktorska disertacija, Odjel za biotehnologiju, Rijeka
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2.Martinović, LovroOtkrivanje ranih neuropatoloških promjena u miševa prenositelja bolesti Niemann-Pick tipa C, 2023., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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3.Katušić Hećimović, SilvaDeciphering molecular links between Alzheimer’s disease and Niemann-Pick type C disease // Joint ICGEB – ALS Society of Canada Symposium on Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder : Abstract Book
Department of Biotechnology, University of Rijeka, 2022. str. 25-25 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
4.Hecimovic, Silva; Dominko, Kristina; Vidatic, Lea; Rastija, AnaDysfunction of the endolysosomal pathway is a common feature of neurodegenerative diseases // FEBS Advanced Course - Molecular targets for anti-aging interventions
Spétses, Grčka, 2022. (pozvano predavanje, podatak o recenziji nije dostupan, neobjavljeni rad, znanstveni) -
5.Dominko, Kristina; Rastija, Ana; Smiljanić, Kosara; Mladenović, Aleksandra; Lešnjaković, Lucija; Kanazir, Selma; Milanović, Desanka; Hećimović, SilvaAmyloid-ß plaque formation and BACE1 accumulation in the brains of a 5xFAD Alzheimer's disease mouse model is associated with altered distribution and not proteolysis of BACE1 substrates Sez6 and Sez6L // Mechanisms of ageing and development, 207 (2022), 111726, 11 doi:10.1016/j.mad.2022.111726 (međunarodna recenzija, članak, znanstveni)
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6.Hecimovic, Silva; Dominko, Kristina; Rastija, Ana; Meglaj, Sarah; Vidatić, Lea; Babić, Andrea; Colombo, Alessio; Tahirovic, Sabina; Hecimovic, SilvaRetromer function is impaired in Niemann-Pick type C disease and is dependent on intracellular cholesterol accumulation // New Horizons in Alzheimer's Disease (Hybrid edition)
Leuven, Belgija, 2021. (poster, međunarodna recenzija, neobjavljeni rad, znanstveni) -
7.Vidatić, Lea; Tipurić, Sandra; Zovko, Ana; Rastija, Ana; Hecimović, SilvaTauopathy in Niemann-Pick type C disease carriers: analysis in a mouse model // 45th FEBS Congress: Molecules of Life: Towards New Horizons (FEBS 2021)
Ljubljana, Slovenija, 2021. (poster, neobjavljeni rad, znanstveni) -
8.Vidatić, Lea; Lichtenthaler, Stefan F.; Tahirović, Sabina; Hećimović, SilvaBACE1 inhibition ameliorates neuroinflammation in organotypic brain slices of Niemann-Pick type C disease murine model // ESGLD Virtual Summer Meeting
Ujedinjeno Kraljevstvo, 2021. (predavanje, neobjavljeni rad, znanstveni) -
9.Dominko, Kristina; Rastija, Ana; Sobočanec, Sandra; Vidatić, Lea; Meglaj, Sarah; Lovinčić Babić, Andrea; Hutter-Paier, Birgit; Colombo, Alessio-Vittorio,; Lichtenthaler, Stefan F.; Tahirović, Sabina; Hećimović, SilvaImpaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation // International journal of molecular sciences, 22 (2021), 24; 13256, 27 doi:10.3390/ijms222413256 (međunarodna recenzija, članak, znanstveni)
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10.Colombo, A; Dinkel, L.; Müller, S. A.; Sebastian Monasor, L.; Schifferer, M.; Cantuti-Castelvetri, L.; König, J.; Vidatić, Lea; Bremova-Ertl, T.; Lieberman, A. et al.Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia // Nature communications, 12 (2021), 1; 1158, 20 doi:10.1038/s41467-021-21428-5 (međunarodna recenzija, članak, znanstveni)
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11.Zovko, AnaPatološke značajke u mozgu miševa nositelja bolesti Niemann-Pick tipa C, 2021., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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12.Meglaj, SarahAnaliza supstrata enzima BACE1 u endosomalnim frakcijama moždanih regija miševa NPC1-/- i divljeg tipa miša (NCP1+/+), 2021., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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13.Hećimović, SilvaThe links between Alzheimer's disease and Niemann-Pick type C disease // Abstracts of papers presented at the 2020 virtual meeting on Neurodegenerative Diseases: Biology & Therapeutics
Lahti: Cold Spring Harbor Laboratory, 2020. str. 154-154 (poster, međunarodna recenzija, sažetak, znanstveni) -
14.Vidatic, Lea; Zovko, Ana; Lasic, Domagoj; Tipuric, Sandra; Rastija, Ana; Hecimovic, SilvaAged mice carriers of a recessive neurodegenerative disorder Niemann-Pick type C show tau hyperphosphorylation, endolysosomal dysfunction and neuroinflammation // Abstracts of papers presented at the 2020 meeting on neurodegenerative diseases : biology & therapeutics
Lahti: Cold Spring Harbor Laboratory, 2020. str. 322-322 (poster, sažetak, znanstveni) -
15.Rastija, Ana; Vidatić, Lea; Tahirović, Sabina; Lichtenthaler, Stefan F.; Hećimović, SilvaCleavage by BACE1 is upregulated in murine primary neurons of a rare neurodegenerative disorder Niemann-Pick type C // Abstracts of papers presented at the 2020 meeting on neurodegenerative diseases : biology & therapeutics
Lahti: Cold Spring Harbor Laboratory, 2020. str. 266-266 (poster, sažetak, znanstveni) -
16.Avrahami, Limor; Paz, Rom; Dominko, Kristina; Hećimović, Silva; Bucci, Cecilia; Eldar-Finkelman, HagitGSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways // Cellular signalling, 71 (2020), 109597, 11 doi:10.1016/j.cellsig.2020.109597 (međunarodna recenzija, članak, znanstveni)
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17.Babić, AndreaKarakterizacija disfunkcije retromernog kompleksa u staničnom modelu bolesti Niemann-Pick tip C, 2020., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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18.Dominko, KristinaUtjecaj unutarstaničnoga kolesterola i C-terminalnoga odsječka proteina prekursora amiloida β na funkciju retromera u modelima Alzheimerove bolesti, 2020., doktorska disertacija, Medicinski fakultet, Zagreb
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19.Dominko, Kristina; Vidatić, Lea; Tahirović, Sabina; Hećimović, SilvaRetromer dysfunction in a rare neurodegenerative disorder Niemann-Pick type C // The 14th International Conference on Alzheimer's & Parkinson's Diseases
Lisabon, Portugal, 2019. (poster, neobjavljeni rad, znanstveni) -
20.Vidatić, Lea; Dominko, Kristina; Rastija, Ana; Pigoni, Martina; Colombo, Alessio, Gunnersen, Jenny M.; Tahirović, Sabina; Lichtenthaler, Stefan F.; Hećimović, SilvaSubcellular localization of BACE1 substrates SEZ6 and SEZ6L is altered in primary neurons of Niemann-Pick type C murine model // The 14th International Conference on Alzheimer's & Parkinson's Diseases
Lisabon, Portugal, 2019. (poster, neobjavljeni rad, znanstveni) -
21.Čaušević, Mirsada; Dominko, Kristina; Malnar, Martina; Vidatic, Lea; Čermak, Stjepko; Pigoni, Martina; Kuhn, Peer-Hendrik; Colombo, Alessio; Havas, Daniel; Flunkert, Stefanie et al.BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains // PLoS One, 13 (2018), 7; e0200344, 22 doi:10.1371/journal.pone.0200344 (međunarodna recenzija, članak, znanstveni)
