Pregled po CROSBI profilu: Nicholas James Bradshaw (CROSBI Profil: 34210, MBZ: 362651, ORCID: 0000-0001-5581-8828)
Pronađeno 82 radova
Prikaz po CROSBI kategorijama
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1.Mapping the Domain Structure and Aggregation Propensity of Proteins Using a Gateway Plasmid Vector System // Protein aggregation: / Cieplak, Andrzej Stanisław (ur.).
New York (NY): Humana Press, 2023. str. 649-677 doi:10.1007/978-1-0716-2597-2_39 -
1.Symptom severity in schizophrenia patients with NPAS3, dysbindin-1 and/or TRIOBP protein pathology in their blood serum: a PANSS-based follow up study // Psychiatria Danubina, 35 (2023), 2; 180-186 doi:10.24869/psyd.2023.180 (međunarodna recenzija, članak, znanstveni)
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2.TRIOBP-1 Protein Aggregation Exists in Both Major Depressive Disorder and Schizophrenia, and Can Occur through Two Distinct Regions of the Protein // International journal of molecular sciences, 23 (2022), 18; 11048, 19 doi:10.3390/ijms231911048 (međunarodna recenzija, članak, znanstveni)
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3.Protein Aggregation of NPAS3, Implicated in Mental Illness, Is Not Limited to the V304I Mutation // Journal of personalized medicine, 11 (2021), 1070, 18 doi:10.3390/jpm11111070 (međunarodna recenzija, članak, znanstveni)
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4.The TRIOBP Isoforms and Their Distinct Roles in Actin Stabilization, Deafness, Mental Illness, and Cancer // Molecules, 25 (2020), 21; 4967, 18 doi:10.3390/molecules25214967 (međunarodna recenzija, pregledni rad, znanstveni)
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5.Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex // Schizophrenia research, 215 (2020), 506-513 (međunarodna recenzija, članak, znanstveni)
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6.Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness // Molecular psychiatry, 24 (2019), 7; 936-951 doi:10.1038/s41380-018-0133-2 (međunarodna recenzija, članak, znanstveni)
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7.Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein // PLoS One, 13 (2018), 1; e0191162, 18 doi:10.1371/journal.pone.0191162 (međunarodna recenzija, članak, znanstveni)
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8.The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression cahnges related to microRNA-484 // Open Biology, 7 (2017), 170153-170153 doi:10.1098/rsob.170153 (međunarodna recenzija, članak, znanstveni)
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9.Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions // Cellular signalling, 40 (2017), 210-221 doi:10.1016/j.cellsig.2017.09.016 (međunarodna recenzija, članak, znanstveni)
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10.NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness // Cellular and molecular life sciences, 74 (2017), 7; 1191-1210 doi:10.1007/s00018-016-2395-7 (međunarodna recenzija, pregledni rad, znanstveni)
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11.A structural organization for the disrupted in schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations // The Journal of biological chemistry, 292 (2017), 16; 6468-6477 doi:10.1074/jbc.M116.773903 (međunarodna recenzija, članak, znanstveni)
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12.An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure // The Journal of biological chemistry, 292 (2017), 23; 9583-9598 doi:10.1074/jbc.M116.767939 (međunarodna recenzija, članak, znanstveni)
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13.Cloning of the promoter of NDE1, a gene implicated in psychiatric and neurodevelopmental disorders through copy number variation // Neuroscience, 324 (2016), 262-270 doi:10.1016/j.neuroscience.2016.03.018 (međunarodna recenzija, članak, znanstveni)
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14.Aggregation of the Protein TRIOBP-1 and Its Potential Relevance to Schizophrenia // PLoS One, 9 (2014), 10; e111196-e111196 doi:10.1371/journal.pone.0111196 (međunarodna recenzija, članak, znanstveni)
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15.Revisiting Disrupted-in-Schizophrenia 1 as a scaffold protein // Biological chemistry, 394 (2013), 11; 1425-1437 doi:10.1515/hsz-2013-0178 (međunarodna recenzija, pregledni rad, znanstveni)
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16.NDE1 and NDEL1: twin neurodevelopmental proteins with similar ‘nature’ but different ‘nurture’ // Biomolecular concepts, 4 (2013), 5; 447-464 doi:10.1515/bmc-2013-0023 (međunarodna recenzija, pregledni rad, znanstveni)
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17.DISC1-binding proteins in neural development, signalling and schizophrenia // Neuropharmacology, 62 (2012), 3; 1230-1241 doi:10.1016/j.neuropharm.2010.12.027 (međunarodna recenzija, pregledni rad, znanstveni)
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18.A t(1 ; 11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins // Human molecular genetics, 21 (2012), 15; 3374-3386 doi:10.1093/hmg/dds169 (međunarodna recenzija, članak, znanstveni)
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19.Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits // Human molecular genetics, 21 (2012), 20; 4406-4418 doi:10.1093/hmg/dds273 (međunarodna recenzija, članak, znanstveni)
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20.The Mitosis and Neurodevelopment Proteins NDE1 and NDEL1 Form Dimers, Tetramers, and Polymers with a Folded Back Structure in Solution // The Journal of biological chemistry, 287 (2012), 39; 32381-32393 doi:10.1074/jbc.M112.393439 (međunarodna recenzija, članak, znanstveni)
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21.Recent and Recurrent Selective Sweeps of the Antiviral RNAi Gene Argonaute-2 in Three Species of Drosophila // Molecular biology and evolution, 28 (2011), 2; 1043-1056 doi:10.1093/molbev/msq280 (međunarodna recenzija, članak, znanstveni)
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22.PKA Phosphorylation of NDE1 Is DISC1/PDE4 Dependent and Modulates Its Interaction with LIS1 and NDEL1 // The Journal of neuroscience, 31 (2011), 24; 9043-9054 doi:10.1523/JNEUROSCI.5410-10.2011 (međunarodna recenzija, članak, znanstveni)
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23.DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness // ACS Chemical Neuroscience, 2 (2011), 11; 609-632 doi:10.1021/cn200062k (međunarodna recenzija, pregledni rad, znanstveni)
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24.NDE1 and NDEL1: Multimerisation, alternate splicing and DISC1 interaction // Neuroscience letters, 449 (2009), 3; 228-233 doi:10.1016/j.neulet.2008.10.095 (međunarodna recenzija, članak, znanstveni)
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25.The DISC locus in psychiatric illness // Molecular psychiatry, 13 (2008), 36-64 doi:10.1038/sj.mp.4002106 (međunarodna recenzija, pregledni rad, znanstveni)
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26.DISC1, PDE4B, and NDE1 at the centrosome and synapse // Biochemical and biophysical research communications, 377 (2008), 4; 1091-1096 doi:10.1016/j.bbrc.2008.10.120 (međunarodna recenzija, članak, znanstveni)
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1.The interaction of schizophrenia-related proteins DISC1 and NDEL1, in light of the newly identified domain structure of DISC1 // Communicative & integrative biology, 10 (2017), 4; e1335375-e1335375 doi:10.1080/19420889.2017.1335375 (podatak o recenziji nije dostupan, komentar, znanstveni)
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2.Corrigendum to "DISC1, PDE4B, and NDE1 at the centrosome and synapse" [Biochem. Biophys. Res. Commun. 377 (2008) 1091–1096] // Biochemical and biophysical research communications, 384 (2009), 3; 400-400 doi:10.1016/j.bbrc.2009.04.057 (podatak o recenziji nije dostupan, ispravak, znanstveni)
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1.Protein aggregation in schizophrenia and other chronic mental illnesses // International Congress of the Croatian Society of Biochemistry and Molecular Biology Abstract Book
Brela, Hrvatska, 2022. str. 30-30 (pozvano predavanje, podatak o recenziji nije dostupan, sažetak, znanstveni) -
2.Determination of the domain structure of DISC1 in mammalian cells identifies a region crucial for its aggregation in schizophrenia // FEBS Open Bio, 12 (Suppl S1)
Lisabon, Portugal, 2022. str. 54-54 (poster, međunarodna recenzija, sažetak, znanstveni) -
3.DISC1 and TRIOBP-1: co-aggregation partners in schizophrenia // Book of Abstracts, 29th International Student Congress Of (bio)Medical Sciences
Groningen, Nizozemska, 2022. str. 436-436 (poster, međunarodna recenzija, sažetak, znanstveni) -
4.Aggregation of NPAS3, involved in schizophrenia, is based on stress // Book of Abstracts, 29th International Student Congress of (bio)Medical Sciences
Groningen, Nizozemska, 2022. str. 369-369 (poster, međunarodna recenzija, sažetak, znanstveni) -
5.Aggregation of the protein TRIOBP-1, involved in schizophrenia, depends on two of its structural regions // Book of Abstracts, 29th International Student Congress of (bio)Medical Sciences
Groningen, Nizozemska, 2022. str. 369-369 (poster, međunarodna recenzija, sažetak, znanstveni) -
6.Aggregation and co-aggregation of specific proteins in postmortem brain samples // SIRS Florence, Italy 2022 Annual Congress Abstract Book
Firenca, Italija, 2022. str. 374-375 (poster, međunarodna recenzija, sažetak, znanstveni) -
7.Determination of the domain structure of DISC1 in mammalian cells identifies a region crucial for its aggregation in schizophrenia // SIRS Florence, Italy 2022 Annual Congress Abstract Book
Firenca, Italija, 2022. str. 376-377 (poster, recenziran, sažetak, znanstveni) -
8.Aggregation of “candidate proteins” for proteinopathy in mental illness // SIRS Florence, Italy 2022 Annual Congress Abstract Book
Firenca, Italija, 2022. str. 85-86 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
9.TRIOBP-1 forms aggregates with other proteins implicated in major mental illness // 8. Croatian Neuroscience Congress, abstract book
Zagreb, Hrvatska, 2021. str. 67-67 (poster, domaća recenzija, sažetak, ostalo) -
10.DISC1 and FUS: linking proteins from mental and neurodegenerative illnesses through aggregation // Abstract book, 10th Student Congress of Neuroscience, Neuri 2021
Rijeka, Hrvatska, 2021. str. 70-71 (predavanje, domaća recenzija, sažetak, ostalo) -
11.Investigating the mechanisms of TRIOBP-1 aggregation in mental illness // Abstract book, 10th Student Congress of Neuroscience, Neuri 2021
Rijeka, Hrvatska, 2021. str. 66-67 (predavanje, domaća recenzija, sažetak, ostalo) -
12.Co-aggregation of proteins involved in mental illness // Abstract book, 10th Student Congress of Neuroscience, Neuri 2021
Rijeka, Hrvatska, 2021. str. 63-64 (predavanje, domaća recenzija, sažetak, ostalo) -
13.Regions of proteins critical to their aggregation in mental illness // Abstract book, 10th Student Congress of Neuroscience, Neuri 2021
Rijeka, Hrvatska, 2021. str. 62-63 (predavanje, domaća recenzija, sažetak, ostalo) -
14.Protein aggregation in major mental illness // Abstract book, 10th Student Congress of Neuroscience, Neuri 2021
Rijeka, Hrvatska, 2021. str. 43-43 (plenarno, domaća recenzija, sažetak, znanstveni) -
15.NPAS3 aggregation, implicated in schizophrenia, is common in post mortem brain samples and can be induced by oxidative stress in neuroblastoma cells // Virtual FENS Regional Meeting 2021 - Book of Abstracts
Krakov: FENS, 2021. str. 256-256 (poster, međunarodna recenzija, sažetak, znanstveni) -
16.NPAS3 aggregation, seen in schizophrenia, is not dependent on a previously reported familial mutation // Mind & Brain - 60th International Neuropsychiatric Congress - Abstract Book (2021) / Demarin, Vida ; Budinčević, Hrvoje (ur.).
Zagreb: International Institute for Brain Health, 2021. str. 60-61 (poster, međunarodna recenzija, sažetak, znanstveni) -
17.Chronic mental illnesses as disorders of protein aggregation // Mind & Brain 59th International Neuropsychiatric Congress. Abstract book 2019.
Pula, Hrvatska, 2019. str. 70-70 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
18.The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to Microrna-484 // European Neuropsychopharmacology, Volume 29, Supplement 3: Abstracts of the XXVth World Congress of Psychiatric Genetics (WCPG)
Orlando (FL), Sjedinjene Američke Države, 2019. str. S914-S914 doi:10.1016/j.euroneuro.2017.08.239 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
19.Protein aggregation and insolubility as a biologial component of chronic mental illness // Psychiatria Danubina (Volume 30, Supplement 1)
Zagreb: Danubian Psychiatic Association, 2018. str. S32-S33 (predavanje, recenziran, sažetak, znanstveni) -
20.Aggregation of specific proteins as a biological component of chronic mental illness // Knjiga apstrakata, IV Kongres psihijatara Bosni i Hercegovine
Banja Luka, Bosna i Hercegovina, 2017. str. 87-87 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
21.Protein aggregation of TRIOBP-1 in patients with schizophrenia // SNC17 Book of Abstractgs
Ljubljana, Slovenija, 2017. str. 59-59 (poster, međunarodna recenzija, sažetak, znanstveni) -
22.TRIOBP-1 aggreation and major mental illness // The 6. Croatian Neuroscience Congress with International Participation, Book of Abstract
Osijek, Hrvatska, 2017. str. 75-75 (poster, recenziran, sažetak, znanstveni) -
23.Protein pathology in chronic mental illness-towards a biological definition // npj Schizophrenia
Firenca, Italija, 2016. str. 160101-2 (predavanje, međunarodna recenzija, sažetak, ostalo) -
24.Phenotypic translation of the DISC1 network highlights the role of the NDE1 locus, with pharmacological implications // European Neuropsychopharmacology, Volume 27, Supplement 3
Jeruzalem, Izrael, 2016. str. S511-2 doi:10.1016/j.euroneuro.2016.09.620 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
25.Functional proteomics backed by genetics and reverse genetic engineering: A novel successful approach to identify schizophrenia subsets // European Neuropsychopharmacology, Volume 27, Supplement 3
Jeruzalem, Izrael, 2016. str. S510-1 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
26.Understanding mental illness from the viewpoint of cellular proteostasis and oxidative stress mechanisms // Biological Psychiatry, Volume 77, Supplement 1
Toronto, Kanada, 2015. 496S, 1 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
27.Domain analysis of TRIOBP-1 implies a common basis underlying its actin polymerization activity and its aggregation in schizophrenia // SfN15 Abstracts PDF Posters 5 Wed PM
Chicago (IL), Sjedinjene Američke Države, 2015. str. 457-458 (poster, međunarodna recenzija, sažetak, znanstveni) -
28.Structural elucidation of DISC1 pathway proteins using electron microscopy, chemical cross-linking and mass spectroscopy // Abstracts of the 3rd Biennial Schizophrenia International Research Conference / Schizophrenia Research 136, Supplement 1
Firenca, Italija, 2012. str. S74-S74 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
1.TRIOBP as a NDE1-interaction partner which may form insoluble aggregates in schizophrenia // Neuroscience 2013
San Diego (CA), Sjedinjene Američke Države, 2017. (poster, međunarodna recenzija, sažetak, znanstveni) -
2.Aggregation of TRIOBP-1 and schizophrenia: Identification of a distinct aggregation domain // 10th FENS Forum of Neuroscience
Kopenhagen, Danska, 2016. (poster, međunarodna recenzija, sažetak, znanstveni) -
3.Aggregation of the protein TRIOBP-1 in schizophrenia // 5th Croatian Neuroscience Congress
Split, Hrvatska, 2015. (predavanje, domaća recenzija, sažetak, znanstveni) -
4.DISC1 and reelin: Linking molecular pathways involved in mental illness // Network Meeting of the Alexander von Humboldt Foundation
Hamburg, Njemačka, 2011. (poster, međunarodna recenzija, sažetak, znanstveni) -
5.DISC1/PDE4-dependent PKA phosphorylation of NDE1 modulates LIS1/NDEL1 binding and neural function // DISC1 2010
Edinburgh, Ujedinjeno Kraljevstvo, 2010. (poster, međunarodna recenzija, sažetak, znanstveni) -
6.PKA phosphorylation of NDE1: Links between DISC1-interacting proteins // The Molecular Basis of Schizophrenia and Bipolar Disorder (X1)
Keystone (CO), Sjedinjene Američke Države, 2009. (poster, međunarodna recenzija, sažetak, znanstveni) -
7.NDE1 interacts with DISC1: A link between schizophrenia-related genes // 15th International Student Congress of Medical Sciences
Groningen, Nizozemska, 2008. (predavanje, međunarodna recenzija, sažetak, znanstveni) -
8.Disrupted-In-Schizophrenia 1 (DISC1) and Protein Kinase A signalling // British Neuroscience Association Meeting 2007
Harrogate, Ujedinjeno Kraljevstvo, 2007. (poster, međunarodna recenzija, sažetak, znanstveni) -
9.NDE1 interacts with DISC1: A link between two schizophrenia-related genes // Neuroscience 2007
San Diego (CA), Sjedinjene Američke Države, 2007. (poster, međunarodna recenzija, sažetak, ostalo) -
1.NDE1 in the DISC1 pathway: interactions of schizophrenia-related proteins, 2009., doktorska disertacija, College of Medicine and Veterinary Medicine, Edinburgh, Velika Britanija
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1.Lijekovima inducirani i genetički modeli miševa manične faze bipolarnog poremećaja, 2021., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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2.Genetsko preklapanje opsesivno-kompulzivnog poremećaja i depresije, 2021., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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3.Uloga DTNBP1/dysbindin-1 u shizofreniji, 2021., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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4.DISC1 i FUS: Koagregacija proteina povezanih s mentalnim i neurodegenerativnim bolestima, 2021., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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5.Proteini interakcijski partneri TRIOBP-1 i njegov učinak na njihovu agregaciju u shizofreniji, 2021., diplomski rad, Odjel za biotehnologiju, Rijeka
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6.Agregacija proteina DISC 1 u mentalnim bolestima, 2020., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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7.Otpornost na agrehaciju mutanata proteina TRIOBP-1 povezanog sa schizofrenijom, 2020., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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8.Modeliranje agregacije proteina NPAS3 i CRMP1 povezanih sa šizofrenijom u stanicama neuroblastoma, 2020., diplomski rad, Odjel za biotehnologiju, Rijeka
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9.Genetska poverzanost između shizofrenije i bipolarnog poremećaja, 2019., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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10.Dokazi povezanosti šizofrenije i poremećaja izazvanih glutenskom prehranom, 2019., diplomski rad, diplomski, Odjel za biotehnologiju, Rijeka
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11.Važnost DISC1 proteina u procesu neurorazvoja, 2019., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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12.Probir proteina koji imaju potencijal agregirati u mentalnim bolestima, 2019., diplomski rad, preddiplomski, Odjel za biotehnologiju, Rijeka
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13.Konvergencija agregiranih proteina prisutnih kod mentalnih bolesti i neurodegenerativnih poremećaja, 2019., diplomski rad, Odjel za biotehnologiju, Rijeka
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14.Defining the aggregation-critical region of the schizophrenia-related protein TRIOBP-1, 2019., diplomski rad, diplomski, Odjel za biotehnologiju, Rijeka
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15.In vitro SUMOilacija proteina povezanih sa mentalnim poremećajima, 2018., diplomski rad, Odjel za biotehnologiju, Rijeka
