Pregled po CROSBI profilu: Nikolina Macek Hrvat (CROSBI Profil: 30546, MBZ: 327424, ORCID: 0000-0003-1682-8999)
Pronađeno 87 radova
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26.Zorbaz, Tamara; Mišetić, Petra; Probst, Nicolas; Žunec, Suzana; Zandona, Antonio; Mendaš, Gordana; Micek, Vedran; Maček Hrvat, Nikolina; Katalinić, Maja; Braïki, Anissa et al.Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning // ACS Chemical Neuroscience, 11 (2020), 7; 1072-1084 doi:10.1021/acschemneuro.0c00032 (međunarodna recenzija, članak, znanstveni)
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27.Maček Hrvat, Nikolina; Kalisiak, Jaroslaw; Šinko, Goran; Radić, Zoran; Sharpless, K. Barry; Taylor, Palmer; Kovarik, ZrinkaEvaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked athrough anti-triazoles, as reactivators of phosphylated cholinesterases // Toxicology letters, 321 (2020), 83-89 doi:10.1016/j.toxlet.2019.12.016 (međunarodna recenzija, članak, znanstveni)
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28.Šagud, Ivana; Maček Hrvat, Nikolina; Grgičević, Ana; Čadež, Tena; Hodak, Josipa; Dragojević, Milena; Lasić, Kornelija; Kovarik, Zrinka; Škorić, IrenaDesign, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives // Journal of enzyme inhibition and medicinal chemistry, 35 (2020), 1; 460-467 doi:10.1080/14756366.2019.1707197 (međunarodna recenzija, članak, znanstveni)
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29.Zorbaz, Tamara; Mišetić, Petra; Žunec, Suzana; Zandona, Antonio; Micek, Vedran; Mendaš, Gordana; Probst, Nicolas; Braïki, Anissa; Maček Hrvat, Nikolina; Katalinić, Maja et al.Pharmacological analysis of centrally active oxime for nerve agent poisoning // Abstract book of the 16th International Symposium on Cholinergic Mechanisms, Rehovot, Izrael
Reẖovot, Izrael, 2019. str. 63-63 (poster, međunarodna recenzija, sažetak, znanstveni) -
30.Kovarik, Zrinka; Maček Hrvat, Nikolina; Žunec, Suzana; Katalinić, MajaDetoxification of Nerve Agents by Oxime-Assisted Reactivation of Cholinesterases // Serbian Biochemical Society Ninth Conference "Diversity in Biochemistry" / Spasojević, Ivan (ur.).
Beograd: Faculty of Chemistry, Serbian Biochemical Society, 2019. str. 39-39 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
31.Kovarik, Zrinka; Maček Hrvat, Nikolina; Žunec, Suzana; Katalinić, MajaDetoxification of tabun-exposed mice by an acetylcholinesterase mutant assisted with a novel pyridinium aldoxime // BIologia Serbica, 41 (2019), 2; 4-8 doi:10.5281/zenodo.3532038 (međunarodna recenzija, članak, znanstveni)
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32.Maček Hrvat, Nikolina; Šagud, Ivana; Čadež, Tena; Ratković, Ana; Škorić, Irena; Kovarik, ZrinkaNew naphthoxazole benzylamines synthesized by Buchwald-Hartwig amination from the electrocyclization photoproducts are potential cholinesterase inhibitors // Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology ˝Crossroads in Life Sciences˝, HDBMB2019, Lovran, Hrvatska, 2019
Lovran, Hrvatska, 2019. str. 98-98 (poster, domaća recenzija, sažetak, znanstveni) -
33.Kovarik, Zrinka; Čadež, Tena; Maček Hrvat, NikolinaAnalysis of Butyrylcholinesterase Interactions with Old Inhibitors and New Reactivators // The FEBS Open Bio, The 44rd FEBS Congress “From molecules to living systems“, Krakow, Poljska
Kraków, Poljska, 2019. str. 431-431 doi:10.1002/2211-5463.12675 (poster, međunarodna recenzija, sažetak, znanstveni) -
34.Kovarik, Zrinka; Zorbaz, Tamara; Maček Hrvat, Nikolina; Čadež, Tena; Žunec, Suzana; Zandona, Antonio; Katalinić, MajaReversal of OP toxicity by the oxime-assisted reactivation of cholinesterases // Abstract book of the 16th International Symposium on Cholinergic Mechanism
Reẖovot, Izrael, 2019. str. 25-25 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
35.Kovarik, Zrinka; Maček Hrvat, Nikolina; Kalisiak, Jarosław; Katalinić, Maja; Sit, Rakesh K.; Zorbaz, Tamara; Radić, Zoran; Fokin, Valery V.; Sharpless, K. Barry; Taylor, PalmerCounteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase // Toxicology and Applied Pharmacology, 372 (2019), 40-46 doi:10.1016/j.taap.2019.04.007 (međunarodna recenzija, članak, znanstveni)
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36.Maček Hrvat, Nikolina; Kalisiak, Jaroslaw; Šinko, Goran; Zandona, Antonio; Radić, Zoran; Sharpless, K. Barry; Taylor, Palmer; Kovarik, ZrinkaDesign and evaluation of phenyltetrahydroisoquinoline pyridinium aldoximes as reactivators of nerve-agent-inhibited human cholinesterases // Abstract book of the 17th Medical Chemical Defense Conference "Chemical Warfare Agents - old problems and new challenges"
München, 2019. str. 138-138 (poster, međunarodna recenzija, sažetak, znanstveni) -
37.Kovarik, Zrinka; Kalisiak, Jarosław; Maček Hrvat, Nikolina; Katalinić, Maja; Zorbaz, Tamara; Žunec, Suzana; Green, Carol; Radić, Zoran; Fokin, Valery V.; Sharpless, Barry K.; Taylor, PalmerReversal of tabun toxicity enabled by a triazole-annulated oxime library - reactivators of acetylcholinesterase // Chemistry - A European Journal, 25 (2019), 16; 4100-4114 doi:10.1002/chem.201805051 (međunarodna recenzija, članak, znanstveni)
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38.Maček Hrvat, Nikolina13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases Hradec Králové, Czech Republic, 9- 14 September 2018 // Arhiv za higijenu rada i toksikologiju, 69 (2018), 3; A46-A47 (domaća recenzija, osvrt, ostalo)
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39.Maček Hrvat, Nikolina; Sit, Rakesh K.; Kovarik, Zrinka; Žunec, Suzana; Green, Carol; Fokin, Valery V; Sharpless, K. Barry; Radić, Zoran; Taylor, PalmerRS194B pharmacokinetics and antidotal potential in mice exposed to VX and sarin // Arhiv za higijenu rada i toksikologiju Vol.69(3)
Zagreb, 2018. str. A23-A23 (predavanje, domaća recenzija, sažetak, znanstveni) -
40.Zorbaz, Tamara; Mišetić, Petra; Maraković, Nikola; Zandona, Antonio; Katalinić, Maja; Maček Hrvat, Nikolina; Braiki, Anissa; Gabelica Marković, Vesna; Jean, Ludovic; Renard, Pierre-Yves; Kovarik, ZrinkaPotent lipophilic 3-hydroxy-2-pyridinium aldoxime reactivators of phosphorylated cholinesterases // Arhiv za higijenu rada i toksikologiju Vol. 69(3)
Zagreb, Hrvatska, 2018. str. A39-A39 (predavanje, domaća recenzija, sažetak, znanstveni) -
41.Maček Hrvat, Nikolina; Green, Carol; Žunec, Suzana; Radić, Zoran; Taylor, Palmer; Kovarik, ZrinkaPost-exposure treatment with the oxime RS194B rapidly reactivates brain acetylcholinesterase activity in mice exposed to sarin and VX // Book of Abstracts of the 10th Congress of Toxicology in Developing Countries and 12th Congress of the Serbian Society of Toxicology
Beograd, Srbija, 2018. str. 154-155 (poster, međunarodna recenzija, sažetak, znanstveni) -
42.Zorbaz, Tamara; Malinak, David; Maraković, Nikola; Maček Hrvat, Nikolina; Zandona, Antonio; Novotny, Michal; Skarka, Adam; Andrys, Rudolf; Benkova, Marketa; Soukup, Ondrej et al.Pyridinium oximes with ortho-positioned chlorine moiety exhibit improved physico- chemical properties and efficient reactivation of human acetylcholinesterase inhibited by several nerve agents // Journal of Medicinal Chemistry, 61 (2018), 23; 10753-10766 doi:10.1021/acs.jmedchem.8b01398 (međunarodna recenzija, članak, znanstveni)
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43.Kovarik, Zrinka; Katalinić, Maja; Maček Hrvat, Nikolina; Šinko, Goran; Zorbaz, Tamara; Bosak, AnitaEnhancement in pyridinium oxime-assisted reactivation of tabun-inhibited acetylcholinesterase achieved by active site mutations // Programme and Abstract Book, Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Republika Češka, 2018 / Korábečný, Jan ; Soukup, Ondrej (ur.).
Hradec Kralove: University of Defence, Faculty of Military Health Sciences, Czech Republic, 2018. str. 35-35 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
44.Zorbaz, Tamara; Mišetić, Petra; Zandona, Antonio; Braiki, Anissa; Maček Hrvat, Nikolina; Katalinić, Maja; Gabelica Marković, Vesna; Jean, Ludovic; Renard, Pierre-Yves; Kovarik, ZrinkaPotent lipophilic reactivators of phosphorylated cholinesterases are not cytotoxic and are metabolically stable // FEBS3+ Conference: From Molecules to Living Systems : Final Programme & Book of Abstracts / Szüts, Dávis ; Buday, László (ur.).
Veszprém: OOK-Press, 2018. str. 89-89 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
45.Maček Hrvat, Nikolina; Kalisiak, Jarosław; Zandona, Antonio; Šinko, Goran; Radić, Zoran; Sharpless, K. Barry; Taylor, Palmer; Kovarik ZrinkaPhenyltetrahydroisoquinoline-based triazole compounds are high- affinity potential reactivators of nerve agent-inhibited human acetylcholinesterase // Programme and Abstract Book, Military Medical Science Letters - Special Issue on the occasion of the 13th International Meeting on Cholinesterases and the 7th International Conference on Paraoxonases, Hradec Králové, Republika Češka, 2018 / Korábečný, Jan ; Soukup, Ondrej (ur.).
Hradec Kralove: University of Defence, Faculty of Military Health Sciences, Czech Republic, 2018. str. 76-76 (poster, međunarodna recenzija, sažetak, znanstveni) -
46.Sit, Rakesh K.; Kovarik, Zrinka; Maček Hrvat, Nikolina; Žunec, Suzana; Green, Carol; Fokin, Valery V.; Sharpless, K. Barry; Radić, Zoran; Taylor, PalmerPharmacology, pharmacokinetics and tissue disposition of zwitterionic hydroxyiminoacetamido alkylamines as reactivating antidotes for organophosphate exposure // The Journal of pharmacology and experimental therapeutics, 367 (2018), 2; 363-372 doi:10.1124/jpet.118.249383 (međunarodna recenzija, članak, znanstveni)
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47.Katalinić, Maja; Šinko, Goran; Maček Hrvat, Nikolina; Zorbaz, Tamara; Bosak, Anita; Kovarik, ZrinkaOxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations // Toxicology, 406-407 (2018), 104-113 doi:10.1016/j.tox.2018.05.008 (međunarodna recenzija, članak, znanstveni)
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48.Zorbaz, Tamara; Braïki, Anissa; Maraković, Nikola; Renou, Julien; de la Mora, Eugenio; Maček Hrvat, Nikolina; Katalinić, Maja; Silman, Israel; Sussman, Joel L; Mercey, Guillaume et al.Potent 3-hydroxy-2-pyridine aldoxime reactivators of organophosphate-inhibited cholinesterases with predicted blood-brain barrier penetration // Chemistry : a European journal, 24 (2018), 38; 9675-9691 doi:10.1002/chem.201801394 (međunarodna recenzija, članak, znanstveni)
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49.Maček Hrvat, Nikolina; Zorbaz, Tamara; Šinko, Goran; Kovarik, ZrinkaThe estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation // Toxicology letters, 293 (2018), 222-228 doi:10.1016/j.toxlet.2017.11.022 (međunarodna recenzija, članak, znanstveni)
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50.Maček Hrvat, Nikolina; Radić, Zoran; Taylor, Palmer; Kovarik, ZrinkaOxime-assisted detoxification of nerve agents by a human AChE mutant // Knjiga Sažetaka Mini simpozija Sekcije za medicinsku i farmaceutsku kemiju. Zagreb, Hrvatska, 2017.
Zagreb, Hrvatska, 2017. str. 3-3 (predavanje, domaća recenzija, sažetak, znanstveni)
