Pregled po CROSBI profilu: Silva Katušić Hećimović (CROSBI Profil: 24514, MBZ: 187522)
Pronađeno 174 radova
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1.Ispitivanje uloge proteaze BACE1 u patogenezi rijetke nasljedne neurodegenerativne Niemann- Pickove bolesti tipa C, 2023., doktorska disertacija, Odjel za biotehnologiju, Rijeka
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2.Otkrivanje ranih neuropatoloških promjena u miševa prenositelja bolesti Niemann-Pick tipa C, 2023., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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3.Deciphering molecular links between Alzheimer’s disease and Niemann-Pick type C disease // Joint ICGEB – ALS Society of Canada Symposium on Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder : Abstract Book
Department of Biotechnology, University of Rijeka, 2022. str. 25-25 (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni) -
4.Dysfunction of the endolysosomal pathway is a common feature of neurodegenerative diseases // FEBS Advanced Course - Molecular targets for anti-aging interventions
Spétses, Grčka, 2022. (pozvano predavanje, podatak o recenziji nije dostupan, neobjavljeni rad, znanstveni) -
5.Amyloid-ß plaque formation and BACE1 accumulation in the brains of a 5xFAD Alzheimer's disease mouse model is associated with altered distribution and not proteolysis of BACE1 substrates Sez6 and Sez6L // Mechanisms of ageing and development, 207 (2022), 111726, 11 doi:10.1016/j.mad.2022.111726 (međunarodna recenzija, članak, znanstveni)
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6.Retromer function is impaired in Niemann-Pick type C disease and is dependent on intracellular cholesterol accumulation // New Horizons in Alzheimer's Disease (Hybrid edition)
Leuven, Belgija, 2021. (poster, međunarodna recenzija, neobjavljeni rad, znanstveni) -
7.Tauopathy in Niemann-Pick type C disease carriers: analysis in a mouse model // 45th FEBS Congress: Molecules of Life: Towards New Horizons (FEBS 2021)
Ljubljana, Slovenija, 2021. (poster, neobjavljeni rad, znanstveni) -
8.BACE1 inhibition ameliorates neuroinflammation in organotypic brain slices of Niemann-Pick type C disease murine model // ESGLD Virtual Summer Meeting
Ujedinjeno Kraljevstvo, 2021. (predavanje, neobjavljeni rad, znanstveni) -
9.Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation // International journal of molecular sciences, 22 (2021), 24; 13256, 27 doi:10.3390/ijms222413256 (međunarodna recenzija, članak, znanstveni)
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10.Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C // Frontiers in Cellular Neuroscience, 15 (2021), 757482, 14 doi:10.3389/fncel.2021.757482 (međunarodna recenzija, članak, znanstveni)
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11.Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia // Nature communications, 12 (2021), 1; 1158, 20 doi:10.1038/s41467-021-21428-5 (međunarodna recenzija, članak, znanstveni)
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12.Patološke značajke u mozgu miševa nositelja bolesti Niemann-Pick tipa C, 2021., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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13.Analiza supstrata enzima BACE1 u endosomalnim frakcijama moždanih regija miševa NPC1-/- i divljeg tipa miša (NCP1+/+), 2021., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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14.Enhanced proteolysis by the Alzheimer's protease BACE1 in NPC1 mouse brains is due to sequestration of its substrates within early endosomes // New Horizons in Alzheimer's Disease (Hybrid edition)
Leuven, Belgija, 2021. str. 157-157 (poster, sažetak, znanstveni) -
15.The links between Alzheimer's disease and Niemann-Pick type C disease // Abstracts of papers presented at the 2020 virtual meeting on Neurodegenerative Diseases: Biology & Therapeutics
Lahti: Cold Spring Harbor Laboratory, 2020. str. 154-154 (poster, međunarodna recenzija, sažetak, znanstveni) -
16.Aged mice carriers of a recessive neurodegenerative disorder Niemann-Pick type C show tau hyperphosphorylation, endolysosomal dysfunction and neuroinflammation // Abstracts of papers presented at the 2020 meeting on neurodegenerative diseases : biology & therapeutics
Lahti: Cold Spring Harbor Laboratory, 2020. str. 322-322 (poster, sažetak, znanstveni) -
17.Cleavage by BACE1 is upregulated in murine primary neurons of a rare neurodegenerative disorder Niemann-Pick type C // Abstracts of papers presented at the 2020 meeting on neurodegenerative diseases : biology & therapeutics
Lahti: Cold Spring Harbor Laboratory, 2020. str. 266-266 (poster, sažetak, znanstveni) -
18.GSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways // Cellular signalling, 71 (2020), 109597, 11 doi:10.1016/j.cellsig.2020.109597 (međunarodna recenzija, članak, znanstveni)
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19.Karakterizacija disfunkcije retromernog kompleksa u staničnom modelu bolesti Niemann-Pick tip C, 2020., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Biološki odsjek, Zagreb
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20.Utjecaj unutarstaničnoga kolesterola i C-terminalnoga odsječka proteina prekursora amiloida β na funkciju retromera u modelima Alzheimerove bolesti, 2020., doktorska disertacija, Medicinski fakultet, Zagreb
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21.Retromer dysfunction in a rare neurodegenerative disorder Niemann-Pick type C // The 14th International Conference on Alzheimer's & Parkinson's Diseases
Lisabon, Portugal, 2019. (poster, neobjavljeni rad, znanstveni) -
22.Subcellular localization of BACE1 substrates SEZ6 and SEZ6L is altered in primary neurons of Niemann-Pick type C murine model // The 14th International Conference on Alzheimer's & Parkinson's Diseases
Lisabon, Portugal, 2019. (poster, neobjavljeni rad, znanstveni) -
23.BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains // PLoS One, 13 (2018), 7; e0200344, 22 doi:10.1371/journal.pone.0200344 (međunarodna recenzija, članak, znanstveni)
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24.Enhanced activity of superoxide dismutase is a common response to dietary and genetically induced increased cholesterol levels // Nutritional neuroscience, 1 (2018), 1; 1-13 doi:10.1080/1028415X.2018.1511027 (međunarodna recenzija, članak, znanstveni)
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25.N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick Type C disease model cells // Molecular & cellular proteomics, 17 (2018), 4; 631-642 doi:10.1074/mcp.RA117.000129 (međunarodna recenzija, članak, znanstveni)
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26.Retromer (dys)function in Niemann-Pick type C disease models // The 6. Croatian Neuroscience Congress with international participation
Osijek, Hrvatska, 2017. str. 77-77 (poster, sažetak, znanstveni) -
27.Uloga poremećaja funkcije lizosoma u metabolizmu prekursora amiloid-beta peptida i homeostazi kolesterola u staničnim i mišjim modelima Niemann-Pickove bolesti tipa C, 2016., doktorska disertacija, Veterinarski fakultet, Zagreb
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28.Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins // PLoS One, 11 (2016), 11; e0167428-1 doi:10.1371/journal.pone.0167428 (međunarodna recenzija, članak, znanstveni)
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29.With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions // Mechanisms of ageing and development, 160 (2016), 54-68 doi:10.1016/j.mad.2016.07.005 (međunarodna recenzija, članak, znanstveni)
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30.Miotonična distrofija tipa 1 // Genetičko informiranje u praksi / Čulić, Vida ; Pavelić, Jasminka ; Radman, Maja (ur.).
Zagreb: Medicinska naklada, 2016. str. 219-222 -
31.Molekularna analiza Huntingtonove bolesti // Genetičko informiranje u praksi / Čulić, Vida ; Pavelić, Jasminka ; Radman, Maja (ur.).
Zagreb: Medicinska naklada, 2016. str. 209-212 -
32.Sindrom fragilnog X // Genetičko informiranje u praksi / Čulić, Vida ; Pavelić, Jasminka ; Radman, Maja (ur.).
Zagreb: Medicinska naklada, 2016. str. 195-198 -
33.Synthesis of new 2-aminoimidazolones with antiproliferative activity via base promoted amino-β-lactam rearrangement // Tetrahedron, 71 (2015), 49; 9202-9215 doi:10.1016/j.tet.2015.10.048 (međunarodna recenzija, članak, znanstveni)
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34.Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors // Bioorganic & medicinal chemistry, 23 (2015), 10; 2353-2359 doi:10.1016/j.bmc.2015.03.067 (međunarodna recenzija, članak, znanstveni)
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35.A Novel PSEN1 Mutation (I238M) associated with Early-Onset Alzheimer's Disease in an African-American Woman // Journal of alzheimers disease, 40 (2014), 2; 271-275 doi:10.3233/JAD-131844 (međunarodna recenzija, članak, znanstveni)
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36.Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors // European journal of medicinal chemistry, 87 (2014), 722-734 doi:10.1016/j.ejmech.2014.10.014 (međunarodna recenzija, članak, znanstveni)
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37.Altered metabolism of BACE1 substrates seizure protein 6 and seizure 6-like protein 1 in Niemann-Pick type C disease // Alzheimer's & Dementia / Schneider, Lon S. (ur.).
New York (NY): Elsevier, 2014. str. P877-P878 (poster, međunarodna recenzija, sažetak, znanstveni) -
38.Izolacija i karakterizacija lizosoma u stanicama CHOwt i CHO NPC1-null, 2014., diplomski rad, diplomski, Farmaceutsko-biokemijski fakultet, Zagreb
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39.Međudjelovanje kolesterola i antioksidativnog sustava, 2014., diplomski rad, diplomski, Prirodoslovno-matematički fakultet, Zagreb
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40.The analysis of presenilin cellular localization in Niemann-Pick type C cells, 2014., diplomski rad, diplomski, Facoltà di Medicina e Chirurgia, Trieste
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41.Isolation and characterization of lysosomes in NPC model cells // FEBS Advanced lecture Course ; 360o Lysosome: from structure to genomics, from function to disease / Zihni Onur Uygun (ur.).
Izmir: Ege University Publishing House, 2014. str. 80-80 (poster, sažetak, znanstveni) -
42.GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells // Biochemical and biophysical research communications, 450 (2014), 1; 160-165 doi:10.1016/j.bbrc.2014.05.083 (međunarodna recenzija, članak, znanstveni)
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43.Cholesterol-mediated oxidative stress in Niemann-Pick type C disease involves a defect in the activity of superoxide dismutase // Book of abstracs Congress of the Croatian Society of Biochemistry and Molecular Biology - HDBMB2014 / KatalinićM., Kovarik Z (ur.).
Zadar: Croatian society for biochemistry and molecular biology, 2014. str. 87-87 (predavanje, međunarodna recenzija, sažetak, znanstveni) -
44.Bidirectional links between Alzheimer's disease and Niemann-Pick type C disease // Neurobiology of disease, 72 (2014), Part A; 37-47 doi:10.1016/j.nbd.2014.05.033 (međunarodna recenzija, pregledni rad, znanstveni)
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45.Niemann-Pick type C disease – a model to study the role of cholesterol in the pathogenesis of Alzheimer's disease // The 19th European Study Group on Lysosomal Diseases (ESGLD
Graz, Austrija, 2013. (poster, međunarodna recenzija, neobjavljeni rad, znanstveni) -
46.The Role of APP in Cholesterol Metabolism: A link between Niemann-Pick type C Disease and Alzheimer's Disease // Workshop MSLife: High Performance Mass Spectrometry: Integration new tools and methods with Applications in Life Sciences
Konstanz, Njemačka, 2013. (pozvano predavanje, neobjavljeni rad, znanstveni) -
47.Utjecaj lipida na patogenezu Alzheimerove bolesti - od molekularnog mehanizma do biomarkera bolesti, 2013., doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb
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48.Cholesterol accumulation in Niemann-Pick type C cells favors APP processing by β-secretase and causes altered endocytic trafficking of BACE1 // Kloster Seeon meeting on BACE proteases in health and disease
Seeon-Seebruck, Njemačka, 2013. (poster, neobjavljeni rad, znanstveni) -
49.Cholesterol Levels Modulate Endosomal Localization of BACE1 // AD/PD 2013 The 11th International Conference On Alzheimer's & Parkinson's Disease
Firenca, Italija, 2013. (poster, sažetak, znanstveni) -
50.Protein Proximity of APP and BACE1 and Membrane Stiffness Is Altered in Different Membranes in Niemann-Pick Type C Disease Cells // AD/PD 2013 The 11th International Conference On Alzheimer's & Parkinson's Disease
Firenca, Italija, 2013. (poster, sažetak, znanstveni)
