Naslov
Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC- EORP EUROASPIRE V survey in 27 countries.

Autori
De Backer , Guy ; Jankowski P ; Kotseva K ; Mirrakhimov E ; Reiner , Željko ; Rydén L ; Tokgözoğlu L ; Wood D ; De Bacquer D ; Kotseva K ; De Backer G ; Abreu A ; Aguiar C ; Badariene J ; Bruthans J ; Castro Conde A ; Cifkova R ; Crowley J ; Davletov K ; Bacquer D ; De Smedt D ; De Sutter J ; Deckers JW ; Dilic M ; Dolzhenko M ; Druais H ; Dzerve V ; Erglis A ; Fras Z ; Gaita D ; Gotcheva N ; Grobbee DE ; Gyberg V ; Hasan Ali H ; Heuschmann P ; Hoes AW ; Jankowski P ; Lalic N ; Lehto S ; Lovic D ; Maggioni AP ; Mancas S ; Marques-Vidal P ; Mellbin L ; Miličić D ; Mirrakhimov E ; Oganov R ; Pogosova N ; Reiner Ž ; Rydén L ; Stagmo M ; Störk S ; Sundvall J ; Tokgözoğlu L ; Tsioufis K ; Vulic D ; Wood D ; Wood DA ; Kotseva K ; Jennings C ; Adamska A ; Adamska S ; Rydén L ; Mellbin L ; Tuomilehto J ; Schnell O ; Druais H ; Fiorucci E ; Glemot M ; Larras F ; Missiamenou V ; Maggioni A ; Taylor C ; Ferreira T ; Lemaitre K ; Bacquer D ; De Backer G ; Raman L ; Sundvall J ; DeSmedt D ; De Sutter J ; Willems AM ; De Pauw M ; Vervaet P ; Bollen J ; Dekimpe E ; Mommen N ; Van Genechten G ; Dendale P ; Bouvier CA ; Chenu P ; Huyberechts D ; Persu A ; Dilic M ; Begic A ; Durak Nalbantic A ; Dzubur A ; Hadzibegic N ; Iglica A ; Kapidjic S ; Osmanagic Bico A ; Resic N ; Sabanovic Bajramovic N ; Zvizdic F ; Vulic D ; Kovacevic-Preradovic T ; Popovic-Pejicic S ; Djekic D ; Gnjatic T ; Knezevic T ; Kovacevic-Preradovic T ; Kos L ; Popovic- Pejicic S ; Stanetic B ; Topic G ; Gotcheva N ; Georgiev B ; Terziev A ; Vladimirov G ; Angelov A ; Kanazirev B ; Nikolaeva S ; Tonkova D ; Vetkova M ; Miličić, Davor ; Reiner , Željko ; Bosnić , Ante ; Dubravčić , Mia ; Glavina , Mihaela ; Mance , Marija ; Pavasović , Saša ; Samardžić , Jure ; Batinic T ; Crljenko K ; Delic-Brkljacic D ; Dula K ; Golubic K ; Klobucar I ; Kordic K ; Kos N ; Nedic M ; Olujic D ; Sedinic V ; Blazevic T ; Pasalic A ; Percic M ; Sikic J ; Bruthans J ; Cífková R ; Hašplová K ; Šulc P ; Wohlfahrt P ; Mayer O Jr ; Cvíčela M ; Filipovský J ; Gelžinský J ; Hronová M ; Hasan-Ali H ; Bakery S ; Mosad E ; Hamed HB ; et al.

Izvornik
Atherosclerosis (Amsterdam) (0021-9150) 285 (2019); 135-146

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Coronary heart disease ; Dyslipidaemia ; EUROASPIRE ; LDL-Cholesterol ; Lipid lowering therapy ; Secondary prevention

Sažetak
BACKGROUND AND AIMS: One of the objectives of the ESC-EORP EUROASPIRE V survey is to determine how well European guidelines on the management of dyslipidaemias are implemented in coronary patients. METHODS: Standardized methods were used by trained technicians to collect information on 7824 patients from 130 centers in 27 countries, from the medical records and at a visit at least 6 months after hospitalization for a coronary event. All lipid measurements were performed in one central laboratory. Patients were divided into three groups: on high-intensity LDL-C- lowering-drug therapy (LLT), on low or moderate-intensity LLT and on no LLT. RESULTS: At the time of the visit, almost half of the patients were on a high-intensity LLT. Between hospital discharge and the visit, LLT had been reduced in intensity or interrupted in 20.8% of the patients and had been started or increased in intensity in 11.7%. In those who had interrupted LLT or had reduced the intensity, intolerance to LLT and the advice of their physician were reported as the reason why in 15.8 and 36.8% of the cases, respectively. LDL-C control was better in those on a high-intensity LLT compared to those on low or moderate intensity LLT. LDL-C control was better in men than women and in patients with self- reported diabetes. CONCLUSIONS: The results of the EUROASPIRE V survey show that most coronary patients have a less than optimal management of LDL-C. More professional strategies are needed, aiming at lifestyle changes and LLT adapted to the need of the individual patient.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA