Naslov
Genetic Classification of Spitzoid Melanoma

Autori
Raghavan, Shyam S. ; Peternel, Sandra ; LeBoit, Philip ; McCalmont, Timothy H. ; Bastian, Boris C. ; Yeh, Iwei

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Izvornik
55th Annual Meeting of The American Society of Dermatopathology, Chicago, USA, 2018 / - , 2018

Skup
55th Annual Meeting of The American Society of Dermatopathology

Mjesto i datum
Chicago (IL), Sjedinjene Američke Države, 08.11.2018. - 11.11.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Malignant Spitz tumor ; Next-generation sequencing ; kinase fusions ; TERT promoter mutations

Sažetak
In the 2018 WHO classification of skin tumours, a new entity, malignant Spitz tumor, is defined as melanoma that harbours one of the initiating alterations that are found in Spitz nevi. It is unclear how often spitzoid melanomas, which are defined solely by their histopathologic features, belong to this new genetically distinct category. We performed high coverage DNA sequencing of 480 cancer related genes in a cohort of spitzoid melanomas.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA