Naslov
Cadmium

Autori
Kostial, Krista

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, pregledni

Knjiga
Trace Elements in Human and Animal Nutrition (Fifth Edition)

Urednik/ci
Mertz, Walter

Izdavač
Academic Press

Grad
Orlando (FL)

Godina
1986

Raspon stranica
319-345

ISBN
0-12-491252-4

Ključne riječi
cadmium in tissues, sources of exposure, cadmium metabolism, health effects

Sažetak
Cadmium is virtually absent from the human body at birth and accumulates with age up to ca. 50 years. It is present in all tissues and fluids, enters in the organism by inhalation and is absorbed via the pulmonary tract in highest rate (up to 60 %), by gastrointestinal system from food (ca. 5 %), taken up from the blood primarily into the liver, distributed in all organs and tissues, stored in kidneys, and excreted in feces and urine. It has very long biological half-life (ca. 10 to >30 years). Cadmium occurs widely in nature, main source of exposure is food and in smokers that is tobacco smoke. It is toxic to virtually every system in the animal body, whether ingested, inhale or injected. Most studied are renal effects, effects on reproduction and development, cardiovascular system and carcinogenic effects. Other well-known effects are on bone, haematopoiesis and immune system. Cadmium interacts with essential elements, mostly zinc, copper, iron and calcium. It induces synthesis of metallothionein in the liver and kidneys.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA