Pregled bibliografske jedinice broj: 996216
A collagen 2 reporter for online identification of chondrogenic microenvironments
A collagen 2 reporter for online identification of chondrogenic microenvironments // eCM XV - Cartilage & Disc: Repair and Regeneration
Davos, Švicarska, 2014. str. 61-61 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 996216 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
A collagen 2 reporter for online identification of chondrogenic microenvironments
Autori
Born, Anne-Kathrin ; Despot Slade, Evelin ; Zenobi-Wong, Marcy
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
ECM XV - Cartilage & Disc: Repair and Regeneration
/ - , 2014, 61-61
Skup
XV European Cells and Materials Meeting
Mjesto i datum
Davos, Švicarska, 16.06.2014. - 18.06.2014
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
cartilage ; collagen 2
Sažetak
Cell-based tissue engineering is a promising method for repair of injured cartilage, however, the outcome depends highly on the continued expression of cartilage markers by the transplanted cells. Collagen 2 is a main structural component of cartilage and hence a method to monitor its expression under changing experimental microenvironments would be of great value. In this study, the human collagen II promoter was cloned into a lentiviral vector and used to drive the expression of green fluorescent protein (GFP) in human chondroprogenitor cells. The resulting promoter reporter gene construct provides the opportunity for non-invasive and repeated imaging of chondrocyte differentiation.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)
