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Pregled bibliografske jedinice broj: 992360

Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays

Blanco, Maria; Pérez-Albaladejo, Elisabet; Pińa, Benjamí; Kušpilić, Grozdan; Milun, Vesna; Lille-Langøy, Roger; Karlsen, Odd André; Goksøyr, Anders; Porte, Cinta
Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays // Science of the total environment, 624 (2018), 1640-1648 doi:10, 1016/j.scitotenv.2017.10.055 (međunarodna recenzija, članak, znanstveni)

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Naslov
Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays

Autori
Blanco, Maria ; Pérez-Albaladejo, Elisabet ; Pińa, Benjamí ; Kušpilić, Grozdan ; Milun, Vesna ; Lille-Langøy, Roger ; Karlsen, Odd André ; Goksøyr, Anders ; Porte, Cinta

Izvornik
Science of the total environment (0048-9697) 624 (2018); 1640-1648

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Sediment ; EROD ; PLHC-1 ; Zebrafish Pxr ; Estrogenic activity ; Kaštela Bay

Sažetak
A battery of cell-based bioassays, including PLHC-1 cells, zebrafish-Pxr-transfected COS-7 cells and estrogen receptor-recombinant yeast assay (ER-RYA), were applied to detect the presence of bioactive pollutants in sediments collected fromKaštela Bay and Brač Channel (Croatia). Exposure of PLHC-1 cells to the sediment extracts evidenced significant cytotoxicity and presence of CYP1A inducers in sediments collected in Kaštela Bay, near the industrial zone and cargo port of Split. Sediments from this area, which is highly contaminated with PCBs, HCB, DDTs and γ-HCH, also activated the zebrafish Pxr (zfPxr) reporter system. No evidence of estrogenicity was detected for any of the sediments extracts in the ER-RYA assay. Importantly, the battery of in vitro assays identified Kaštela Bay as the area with the higher anthropogenic impact, where sediment-bound pollutants could pose a risk to aquatic organisms. In contrast, sediments fromthe Brač Channel showed rather lowresponse in the different bioassays.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Interdisciplinarne prirodne znanosti



POVEZANOST RADA

Ustanove:
Institut za oceanografiju i ribarstvo, Split

Profili:

Avatar Url Vesna Milun (autor)

Avatar Url Grozdan Kušpilić (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com

Citiraj ovu publikaciju:

Blanco, Maria; Pérez-Albaladejo, Elisabet; Pińa, Benjamí; Kušpilić, Grozdan; Milun, Vesna; Lille-Langøy, Roger; Karlsen, Odd André; Goksøyr, Anders; Porte, Cinta
Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays // Science of the total environment, 624 (2018), 1640-1648 doi:10, 1016/j.scitotenv.2017.10.055 (međunarodna recenzija, članak, znanstveni)
Blanco, M., Pérez-Albaladejo, E., Pińa, B., Kušpilić, G., Milun, V., Lille-Langøy, R., Karlsen, O., Goksøyr, A. & Porte, C. (2018) Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays. Science of the total environment, 624, 1640-1648 doi:10, 1016/j.scitotenv.2017.10.055.
@article{article, author = {Blanco, Maria and P\'{e}rez-Albaladejo, Elisabet and Pi\'{n}a, Benjam\'{\i} and Ku\v{s}pili\'{c}, Grozdan and Milun, Vesna and Lille-Lang\oy, Roger and Karlsen, Odd Andr\'{e} and Goks\oyr, Anders and Porte, Cinta}, year = {2018}, pages = {1640-1648}, DOI = {10, 1016/j.scitotenv.2017.10.055}, keywords = {Sediment, EROD, PLHC-1, Zebrafish Pxr, Estrogenic activity, Ka\v{s}tela Bay}, journal = {Science of the total environment}, doi = {10, 1016/j.scitotenv.2017.10.055}, volume = {624}, issn = {0048-9697}, title = {Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays}, keyword = {Sediment, EROD, PLHC-1, Zebrafish Pxr, Estrogenic activity, Ka\v{s}tela Bay} }
@article{article, author = {Blanco, Maria and P\'{e}rez-Albaladejo, Elisabet and Pi\'{n}a, Benjam\'{\i} and Ku\v{s}pili\'{c}, Grozdan and Milun, Vesna and Lille-Lang\oy, Roger and Karlsen, Odd Andr\'{e} and Goks\oyr, Anders and Porte, Cinta}, year = {2018}, pages = {1640-1648}, DOI = {10, 1016/j.scitotenv.2017.10.055}, keywords = {Sediment, EROD, PLHC-1, Zebrafish Pxr, Estrogenic activity, Ka\v{s}tela Bay}, journal = {Science of the total environment}, doi = {10, 1016/j.scitotenv.2017.10.055}, volume = {624}, issn = {0048-9697}, title = {Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays}, keyword = {Sediment, EROD, PLHC-1, Zebrafish Pxr, Estrogenic activity, Ka\v{s}tela Bay} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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