Pregled bibliografske jedinice broj: 991953
MMP-9 triggered micelle-to-fibre transitions for slow release of doxorubicin
MMP-9 triggered micelle-to-fibre transitions for slow release of doxorubicin // Biomaterials Science, 3 (2015), 2; 246-249 doi:10.1039/c4bm00297k (međunarodna recenzija, članak, znanstveni)
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Naslov
MMP-9 triggered micelle-to-fibre transitions for slow release of doxorubicin
Autori
Kalafatovic, Daniela ; Nobis, Max ; Javid, Nadeem ; Frederix, Pim W. J. M. ; Anderson, Kurt I. ; Saunders, Brian R. ; Ulijn, Rein V.
Izvornik
Biomaterials Science (2047-4830) 3
(2015), 2;
246-249
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Peptides ; Self-assembly ; MMP
Sažetak
Phenylacetyl-peptide amphiphiles were designed, which upon cleavage by a disease-associated enzyme reconfigure from micellar aggregates to fibres. Upon this morphological change, a doxorubicin payload could be retained in the fibres formed, which makes them valuable carriers for localised formation of nanofibre depots for slow release of hydrophobic anticancer drugs.
Izvorni jezik
Engleski
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE