Naslov
Development of medical products based on human plasma

Autori
Josić, Đuro ; Pock, Katharina

Izvornik
Food technology and biotechnology (1330-9862) 37 (1999), 1; 51-63

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
human plasma ; product development

Sažetak
Product development and process validation are shown in the case of several products obtained from human plasma. These are virus inactivated plasma, intravenous immunoglobulins and the clotting factors VIII and IX. Different analytical methods are presented, which are used for product development, quality control and in-process control. The introduction of fast chromatographic methods allows in-process analyses to be carried out within two or three minutes only. Analytical methods with high resolution such as 2D-electrophoresis will lead to corresponding results even in the case of components with high molecular masses such as clotting factor VIII and von Willebrand factor. These methods have recently been introduced into the process.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA