Naslov
The Role Of Ki-67 In Oral Leukoplakia-Review Article

Autori
Žužul, Ivona ; Andabak Rogulj, Ana ; Terlević, Diana ; Pavić, Ivana ; Granić, Marko ; Vuletić, Marko ; Jerković, Daniel

Izvornik
Research journal of pharmaceutical, biological and chemical sciences (0975-8585) 10 (2019), 2; 36-40

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
Ki-67 ; leukoplakia ; malignant potential ; biomarker

Sažetak
Leukoplakia is the most common oral precancerous lesion which might evolve into oral cancer. Apart from the usual histopathology which shows the degree of dysplasia there are no other reliable marker(s) which would depict which lesions will develop into oral cancer. So far, the role of Ki-67 in oral leukoplakia has been extensively investigated. Therefore, we searched Pubmed regarding the role of Ki-67 in oral leukoplakia in the last 25 years and 30 articles were retrieved. The results of this review suggest that Ki-67 seems to be very reliable immunohistochemical marker for malignant progression.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA