Performance of the COMPASS-31 questionnaire with regard to autonomic nervous system testing results and medication use: a prospective study in a real-life setting

Ruška, Berislav; Pavičić, Tin; Pavlović, Ivan; Junaković, Anamari; Adamec, Ivan; Crnošija, Luka; Krbot Skorić, Magdalena; Habek, Mario

doi:10.1007/s10072-018-3542-8

Pregled bibliografske jedinice broj: 986000

Performance of the COMPASS-31 questionnaire with regard to autonomic nervous system testing results and medication use: a prospective study in a real- life setting

Ruška, Berislav; Pavičić, Tin; Pavlović, Ivan; Junaković, Anamari; Adamec, Ivan; Crnošija, Luka; Krbot Skorić, Magdalena; Habek, Mario

Performance of the COMPASS-31 questionnaire with regard to autonomic nervous system testing results and medication use: a prospective study in a real- life setting // Neurological sciences, 39 (2018), 12; 2079-2084 doi:10.1007/s10072-018-3542-8 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 986000 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Performance of the COMPASS-31 questionnaire with regard to autonomic nervous system testing results and medication use: a prospective study in a real- life setting

Autori
Ruška, Berislav ; Pavičić, Tin ; Pavlović, Ivan ; Junaković, Anamari ; Adamec, Ivan ; Crnošija, Luka ; Krbot Skorić, Magdalena ; Habek, Mario

Izvornik
Neurological sciences (1590-1874) 39 (2018), 12; 2079-2084

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
autonomic nervous system ; COMPASS-31 ; medications

Sažetak
The aim of this study was to investigate the performance of the Composite Autonomic System Score-31 (COMPASS-31) questionnaire in a real- life setting in consecutive patients referred to the laboratory for objective testing of the autonomic nervous system (ANS), with the hypothesis that COMPASS-31 results differ depending on medications and findings of the tilt table test results. One hundred seventy- one consecutive patients (125 females, mean age 41.5 ± 19.3) referred for testing of the ANS were enrolled. Before testing, all patients completed the recently validated Croatian version of COMPASS-31. The following data were systematically collected for all patients: age, sex, diagnoses, and medications. Results of COMPASS-31 were significantly higher in patients taking medications with a known influence on the ANS (p < 0.001). Patients with postural orthostatic tachycardia had significantly higher orthostatic intolerance and vasomotor domains of COMPASS-31 (p = 0.048 and p = 0.022, respectively). Patients with a cardiovagal score ≥ 1 had a significantly higher vasomotor domain of COMPASS-31 compared to patients with normal results of ANS tests (p = 0.030). These findings suggest the COMPASS-31 might be a valuable screening tool for autonomic dysfunctions, as it is associated with impaired ANS tests, but usage of medications that modify the ANS should always be taken into account.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA

Ustanove:
Fakultet elektrotehnike i računarstva, Zagreb,
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Profili:

MAGDALENA KRBOT SKORIĆ (autor)