Naslov
Psychological stress in patients with atopic dermatitis

Autori
Meštrović-Štefekov, Jelena ; Novak-Bilić, Gaby ; Kuna, Matea ; Pap, Nives ; Lugović Mihić, Liborija

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 26 (2018), 4; 297-303

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
atopic dermatitis, psychological stress, cortisol, immune factors, psychoneuroimmunology

Sažetak
Atopic dermatitis (AD) is a frequent dermatosis with a growing incidence and multifactorial and complex pathogenic mechanisms that are still being investigated. Although the connection between AD and psychological stress has been known for a long time, there is a lack of reliable and objective indicators for the characterization of this association.Psychological stress triggers complex immune pathways.Therefore acute stress quickly triggers complex a high release of cortisol and adrenalin or noradrenalin wich then stimulates the immune system, primarly T-helper type (Th1 cells) to produce pro-inflammatory cytokines, resulting in a cellular immune response and inflammation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA