Naslov
Comparison of different in vitro tools for prediction of intestinal permeability of olive- derived nutraceuticals

Autori
Radić, Kristina ; Jurišić Dukovski, Bisera ; Lovrić, Jasmina ; Lisičar, Marina ; Vitali Čepo, Dubravka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Second All WGs UNGAP Meeting / - , 2019, 1-2

Skup
UNGAP SPRING MEETING

Mjesto i datum
Sofija, Bugarska, 12.02.2019. - 13.02.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Olive pomace ; bioavailability ; tyrosol ; hydroxytyrosol ; Caco-2 ; PAMPA

Sažetak
Olive pomace has a composition very similar to olive oil. Thus, it may exert biological effects comparable to those of olive oil (antioxidative, antinflammatory, etc.). However, in complex matrices, such as olive pomace extract (OPE), bioavailability is largely dictated by the release of active ingredients from matrix during the digestion process. Therefore, we simulated in vitro digestion of OPE encapsulated with several cyclodextrins and predicted intestinal permeability of hydroxytyrosol and tyrosol (main olive phenolic compounds).

Izvorni jezik
Engleski

POVEZANOST RADA