Pregled bibliografske jedinice broj: 984584
Bethesda thyroid categories and family history of thyroid disease
Bethesda thyroid categories and family history of thyroid disease // Clinical endocrinology, 88 (2018), 3; 468-472 doi:10.1111/cen.13538 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 984584 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Bethesda thyroid categories and family history of
thyroid disease
Autori
Kust, Davor ; Staničić, Josip ; Mateša, Neven
Izvornik
Clinical endocrinology (0300-0664) 88
(2018), 3;
468-472
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Bethesda system ; cytological finding ; familial thyroid cancer ; family history ; papillary thyroid cancer ; thyroid cancer ; thyroid disease
Sažetak
Objective:Thyroid cancer is the most common type of endocrine-related cancer worldwide. The aim of this article was to assess the relationship between thyroid diseases diagnosed by fine needle aspiration (FNA) and family history of thyroid disease. DesignThe study was conducted in a tertiary high- volume thyroid cancer centre. Fine needle aspiration (FNA) of a thyroid nodule detected on neck ultrasound for any reason was performed in all included patients. Patients A total of 10709 patients were included in the study. Measurements Correlation of cytological findings classified according to the Bethesda system and family history was calculated using Fisher's exact test. ResultsThere were 2580 (24.09%) patients with non-malignant thyroid diseases in the family and 198 (1.85%) patients who had a history of thyroid cancer in the family. A total of 2778 (25.94%) patients had positive family history of thyroid diseases, and 7931 (74.06%) patients had negative family history. In patients with papillary thyroid carcinoma in family history, the difference between those with benign (Bethesda 2) and malignant thyroid FNA diagnosis (Bethesda 6) was found to be statistically significant (P=.0432). ConclusionsFamily history plays a significant role in the development of thyroid cancer, and having first-degree relatives with not only medullary, but also papillary thyroid cancer strongly predicts the risk of developing the malignant thyroid disease. In contrast, benign thyroid disorders in family history do not lead to the development of thyroid cancer.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
