Naslov
The Level of Depression in Parkinson's Disease Patients

Autori
Trkanjec, Zlatko ; Martinic Popovic, Irena ; Šeric, Vesna ; Mikula, Ivan ; Podobnik Sarkanji, Slava ; Demarin, Vida.

Izvornik
Journal of the neurological sciences (0022-510X) 187 (2001), 1; 394-394

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Parkinson's disease; depression

Sažetak
Background: Depression is the most common neuropsychiatric disturbance in Parkinson's disease. Objective: The objective of this study was to detect whether the severity of motor symptoms contributes to the incidence of depression in patients with PD. Methods: 21 males and 9 females patients (pts) with classic type of idiopathic Parkinson's disease (mean age 64, 6, range 44-76 years lyn. According to age pts were divided in three groups: <55 y, 55-64 y of age, and >65 y. The severity of parkinsonian symptoms was assessed using the Hohn and Yahr Scale (H&Y). Schwab and England Activities of Daily Living Scale (ADL) was used in order to estimate disability due to disease. Pts were divided according to H&Y in two groups: less severe (H&Y<3) and more severe stage of disease (H&Y>=3), and according to ADL in three groups: mildly (ADL=80-100%), moderately (ADL=60-79%) and severely disabled (ADL<60%). The level of depression was estimated using the Montgomery Aasberg Depression Rating Scale (MADRS). According to MADRS pts were divided in three groups: mild (MADRS<10), moderate (MADRS=10-20) and severe depression (MADRS>20). Results: 6 pts were younger <55 y, 8 pts aged 55-65 y and 16 pts were older >65 y. The number of pts in mild depressive group declined in older groups. The number of pts with moderate depression increased in older groups. There were 12 pts with H&Y<3, and 18 pts with H&Y>=3. The majority of pts with H&Y>=3 were in oldest group (11 pts were older >65 y). Pts with H&Y<3 were either mild (7) or moderate (5) depressive, while pts with H&Y>=3 were mild (2), moderate (12) and severe (4) depressive. According to ADL there were 5 mildly disabled, 11 moderately disabled and 14 severely disabled pts. Mildly disabled pts were either mild (3) or moderate depressive (2) ; moderately disabled pts were mild (6), moderate (4) and severe (1) depressive, while severely disabled pts were either moderate (11) or severe (3) depressive. Conclusion: Less severe pts had mild and moderate depression, while more severe pts had predominantly moderate and severe depression. Disability in everyday activities measured by ADL, showed that majority of pts with severe disability had moderate and severe forms of depression. These findings indicate that depressive symptoms in pts with PD could be the result of disease progression, as well as the consequence of physical disability caused by disease itself

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA