Naslov
CD23 molecule in sera of atopic dermatitis patients

Autori
Lipozenčić, Jasna ; Lugović, Liborija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstracts of the 21st Congress of the European Academy of Allergology and Clinical Immunology : (EAACI 2002) ; u: Allergy. Supplement 57 (2002) S73 (Poster Discussion Session 11: Atopic dermatitis and urticaria 300-304 ; P981) / - , 2002, 301-302

Skup
Congress of the European Academy of Allergology and Clinical Immunology : (21 ; 2002)

Mjesto i datum
Napulj, Italija, 01.06.2002. - 05.06.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
molecule CD23; B lymphocytes; total serum IgE; atopic dermatitis

Sažetak
CD23 is multifactorial molecule and low affinity receptor for IgE, and is capable for regulating the synthesis of human IgE. It is known that CD23+ cells are increased in the patients with atopic dermatitis (AD). The aim of the study was correlation of some important parameters in diagnosis of atopic dermatitis: total serum IgE, CD23, CD4 levels, and skin tests. In the study of 40 AD patients and 20 healthy subject were measured the expression of CD23 on peripheral blood B-lymphocytes, CD4 levels, values of total IgE and results of skin prick and scratch tests. The results showed mostly normal expression of CD23 (30/40) with high expression of CD23 in 10 out of 40 AD patients. We noted that AD patients had higher percentage of CD33+ cells then healthy controls. The results of skin tests correlated positively with total serum IgE. There was no correlation between CD23, CD4 levels and total serum IgE.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Napomena
10.1034/j.1398-9995.57.s73.142.x

POVEZANOST RADA