Pregled bibliografske jedinice broj: 978184
Ready-to-use green polyphenolic extracts from food by-products
Ready-to-use green polyphenolic extracts from food by-products // Food chemistry, 283 (2019), 628-636 doi:10.1016/j.foodchem.2019.01.061 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 978184 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Ready-to-use green polyphenolic extracts from food by-products
Autori
Panić, Manuela ; Radić Stojković, Marijana ; Kraljić, Klara ; Škevin, Dubravka ; Radojčić Redovniković, Ivana ; Gaurina Srček, Višnja ; Radošević, Kristina
Izvornik
Food chemistry (0308-8146) 283
(2019);
628-636
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
biological activities ; grape pomace ; natural deep eutectic solvents ; olive pomace ; polyphenolic compounds
Sažetak
To establish environmentally friendly polyphenolic extracts from grape and olive pomace, natural deep eutectic solvents (NADES) were used coupled with alternative energy sources – ultrasound and microwave irradiation. Obtained extracts were characterized by HPLC analysis, while antioxidant capacity was determined by ORAC method. Furthermore, in vitro cytotoxicity of prepared extracts was assessed by antiproliferation assay on two tumour cell lines, whereas for investigation of type of cell death or cell cycle arrest a flow cytometric analysis was applied. In addition, a detection of compounds with DNA/RNA-binding affinity in extracts was investigated by UV/Vis and circular dichroism spectroscopy. Grape pomace extract in NADES showed to be the best of all extracts tested, with regard to extraction of total polyphenolic compounds (p<0.05) and related biological activities such as antioxidant and antiproliferative activity. Prepared polyphenolic extracts in NADES could be considered as ready-to-use in food and pharmaceutical industry without demanding and expensive downstream purification steps.
Izvorni jezik
Engleski
Znanstvena područja
Biotehnologija
POVEZANOST RADA
Projekti:
IP-2014-09-9550 - Zelena otapala za zelene tehnologije (GREEN) (Radojčić Redovniković, Ivana, HRZZ - 2014-09) ( CroRIS)
--IP-2018-01-4694 - Molekularno prepoznavanje DNA:RNA hibridnih i višelančanih struktura u bioanalitičkim i in vitro sustavima (DNARNAHyB-MolBio) (Radić Stojković, Marijana) ( CroRIS)
Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb
Profili:
Kristina Radošević
(autor)
Višnja Gaurina-Srček
(autor)
Ivana Radojčić Redovniković
(autor)
Dubravka Škevin
(autor)
Klara Kraljić
(autor)
Marijana Radić Stojković
(autor)
Manuela Panić
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE