Pregled bibliografske jedinice broj: 972198
Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics
Amino-β-lactams in Ugi reaction: An efficient method for preparation of functionalized peptidomimetics // Tetrahedron, 74 (2018), 52; 7495-7506 doi:10.1016/j.tet.2018.11.028 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 972198 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Amino-β-lactams in Ugi reaction: An efficient method
for preparation of functionalized peptidomimetics
Autori
Vazdar, Katarina ; Jerić Ivanka
Izvornik
Tetrahedron (0040-4020) 74
(2018), 52;
7495-7506
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Ugi reaction ; Amino-β-lactams ; Peptidomimetics
Sažetak
A synthetic strategy for the Ugi reaction on amino-β- lactam synthon 1 was developed. The Ugi reaction products 5 were obtained in satisfactory yields (47– 78%) and generally, low diastereoselectivity (up to 72:28 dr). In case of Ugi products 5 derived from cyclohexylcarbaldehyde and amino-β-lactam 1, the reaction yields were lower (38–61%) but the products were obtained in high diastereoselectivity (>95:5).
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
HRZZ-IP-2014-09-3102 - Višekomponentne reakcije u sintezi peptidnih mimetika (MIMICRy) (Jerić, Ivanka, HRZZ - 2014-09) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- BIOSIS Previews (Biological Abstracts)
