Naslov
High prevalence of diabetic retinopathy in patients with type diabetes and normal renal function

Autori
Šmaguc, Ana ; Bulum, Tomislav ; Tomić, Martina ; Vrabec, Romano ; Duvnjak, Lea

Izvornik
Diabetologia Croatica (0351-0042) 46 (2017), 2; 33-38

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
type 1 diabetes ; albuminuria ; retinopathy

Sažetak
The most important microvascular complications in patients with diabetes occur at the same time and that the severity of retinopathy parallels the presence and severity of nephropathy in diabetes mellitus. The aim of this study was to evaluate the prevalence of retinopathy in patients with type 1 diabetes mellitus (T1DM) and normal renal function. A total of 333 T1DM patients with normal renal function (estimated glomerular filtration rate (eGFR) >60 mLmin-11.73 m2 and normoalbuminuria) were included in the study (age 38±7 years, 160 M/173 F, body mass index 23±5 kg/m2, hemoglobin A1c (HbA1c) 7.5±1.5%, duration of diabetes 16±8 years, serum creatinine 70±12 μmol/L, eGFR 108±15 mLmin-11.73 m2, urinary albumin excretion rate 10.8 (1.7-29.8 mg/24 h). The majority of patients (60%) were without retinopathy (the majority of those with retinopathy (84%) had nonproliferative retinopathy). Patients with proliferative and nonproliferative retinopathy compared to patients without retinopathy were older, had longer duration of diabetes, had higher HbA1c, higher total cholesterol, higher LDL- cholesterol, higher resting heart rate, and lower eGFR. The results of our study suggested a high prevalence of retinopathy in T1DM with normal renal function, especially in older patients with longer duration of diabetes, higher HbA1c, total and LDL cholesterol, resting heart rate and lower eGFR.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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