Pregled bibliografske jedinice broj: 967824
Flavonoid Biosynthetic Pathways in Plants: Versatile Targets for Metabolic Engineering
Flavonoid Biosynthetic Pathways in Plants: Versatile Targets for Metabolic Engineering // Biotechnology advances, 38 (2020), 107316, 12 doi:10.1016/j.biotechadv.2018.11.005 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 967824 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Flavonoid Biosynthetic Pathways in Plants: Versatile Targets for Metabolic Engineering
Autori
Nabavi, Seyed Mohammad ; Šamec, Dunja ; Tomczyk, Michał ; Milella, Luigi ; Russo, Daniela ; Habtemariam, Solomon ; Suntar, Ipek ; Rastrelli, Luca ; Daglia, Maria ; Xiao, Jianbo ; Giampieri, Francesca ; Battino, Maurizio ; Sobarzo-Sanchez, Eduardo ; Jeandet, Philippe ; Nabavi, Seyed Fazel ; Yousefi, Bahman ; Xu, Suowen ; Shirooie, Samira
Izvornik
Biotechnology advances (0734-9750) 38
(2020);
107316, 12
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
Flavonoids ; Shikimic acid ; Acetate ; Metabolic engineering
Sažetak
Plants, fungi, and microorganisms are equipped with biosynthesis machinery for producing thousands of secondary metabolites. These compounds have important functions in nature as a defense against predators or competitors as well as other ecological significances. The full utilization of these compounds for food, medicine, and other purposes requires a thorough understanding of their structures and the distinct biochemical pathways of their production in cellular systems. In this review, flavonoids as classical examples of secondary metabolites are employed to highlight recent advances in understanding how valuable compounds can be regulated at various levels. With extensive diversity in their chemistry and pharmacology, understanding the metabolic engineering of flavonoids now allows us to fine-tune the eliciting of their production, accumulation, and extraction from living system. More specifically, recent advances in the shikimic acid and acetate biosynthetic pathways of flavonoids production from metabolic engineering point of view, from genes expression to multiple principles of regulation, are addressed. Specific examples of plants and microorganisms as the sources of flavonoids-based compounds with particular emphasis on therapeutic applications are also discussed.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Biotehnologija
POVEZANOST RADA
Projekti:
UKF-12/17
HRZZ-IP-2014-09-4359 - Fitohormoni u abiotskom stresu kupusnjača: mehanizam tolerancije i primjena (PhytoBraCro) (Salopek-Sondi, Branka, HRZZ - 2014-09) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Dunja Šamec
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE