Naslov
Comparison of normal saline and balanced crystalloid intravenous therapy during neurosurgery

Autori
Kovač, Nataša ; Mladić Batinica, Inga ; Kukin, Dijana ; Murselović, Tamara ; Tonković Dinko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
European Journal of Anaesthesiology / - , 2018

Skup
19th European Conference on Analytical Chemistry (EuroAnalysis 2018)

Mjesto i datum
Kopenhagen, Danska, 02.06.2018. - 05.06.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Neurosurgery, normal saline fluid, balanced fluid

Sažetak
Normal saline or 0.9% NaCl solution is the most commonly used intravenous fluid worldwide and its composition are 154 mmol Na+ and 154 mmol Cl- per litter with osmolarity of 308 mOsmol/L. That composition is not “normal” because plasma contains sodium in range between 137-146 mmol/L, and chloride in range between 98-106 mmol/L, with plasma osmolality of 280- 295 mOsmol/kg. Recently published data suggested detrimental effects of chloride rich fluids on renal blood flow and glomerular filtration rate, urine output and acute kidney injury. One alternative to saline solution is a buffered, balanced, crystalloid solution with an electrolyte composition similar to plasma and osmolarity between 286-295 mOsmol/L. Someone could indicate that such balanced solutions are not suitable for neurosurgical patients because of a possible impact on the brain oedema development.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA