Naslov
Agents acting on the renin-angiotensin system: Usage in Croatia during a seven-year period

Autori
Vitezić, Dinko ; Matana Kaštelan, Zrinka ; Buble, Tonći ; Vitezić, Miomira ; Kovačević, Miljenko ; Mršić-Pelčić, Jasenka ; Župan, Gordana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Value in Health, Vol 12 (7) / - , 2009, 343-343

Skup
Twelfth Annual European Congress

Mjesto i datum
Pariz, Francuska, 24.10.2009. - 27.10.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Agents ; Renin-angiotensin system ; Croatia ; Seven-year period

Sažetak
OBJECTIVES: In the contemporary world, particularly in developing countries, cardiovascular (CV) diseases are a major health care problem. Agents acting on the renin- angiotensin system (RAS) have an important place in the management of these diseases. METHODS: The data concerning drugs usage prescribed by GPs during the period from 2001 to 2007 were collected from the Croatian Health Insurance Institute. Annual volumes of drugs are presented in defined daily doses/1000 inhabitants/day (DDD/1000), while financial expenditure data are presented in Euros (a). An average cost per DDD was calculated for this group of drugs. RESULTS: Agents acting on the RAS for the seven-year period remained the most prescribed CV drug group with the largest cost share. The use of the whole group increased 115% (from 56.07 to 120.55 DDD/1000) while the related expenses increased 53.5%. The consumption and cost shares of ACE inhibitors (plain and combined) decreased (from 98% to 88% and from 96% to 90%, respectively). The use of the combinations of ACE inhibitors and diuretics increased from 10.07 to 41.90 DDD/1000 and angiotensin receptor blockers and diuretics from 0 to 6.42 DDD/1000. The average cost per DDD for the investigated group dropped from 0.33 to 0.24 a/DDD. CONCLUSIONS: During the investigated period the usage of the group of agents acting on the RAS increased considerably. The related growth of financial expenditure increased at a slower rate. The average cost per DDD gradually decreased mainly as the result of the introduction of generics and the implementation of restrictive measures on the Croatian drug market.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA