Naslov
Purification Processes Of Xenogeneic Bone Substitutes And Their Impact On Tissue Reactions And Regeneration

Autori
Perić Kačarević, Željka ; Kavehei, Faraz ; Jung, Ole ; Smeets, Ralf ; Rimashevskiy, Denis ; Wenisch, Sabine ; Schnettler Reinhard ; Barbeck, Mike

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
The International Journal of Artificial Organs / - , 2018, 486-631

Skup
45th ESAO Congress

Mjesto i datum
Madrid, Španjolska, 12.09.2018. - 15.09.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Bone substitute, xenograft, multinucleated giant cells, implant bed vascularization, inflammation

Sažetak
Xenogeneic bone substitute materials are widely used in oral implantology. Prior to their clinical use, a purification of the former bone tissue has to be conducted to ensure the removal of immunogenic components and pathogens. Different physicochemical methods are applied for the purification of the donor tissue and temperature treatment is one of these methods. Differences in these methods and especially the application of different temperatures for purification may lead to different material characteristics, which may influence the tissue reactions to these materials and the related (bone) healing process. However, little is known about the different material characteristics and their influences on the healing process. Thus, the aim of the present mini-review is to summarize the preparation processes and the related material characteristics, the safety aspects, the tissue reactions, the resorbability and the preclinical and clinical data oftwo widely used xenogeneic bone substitutes that mainly differ in the temperature treatment, i.e., sintered (cerabone) and non-sintered (Bio-Oss) bovinebone materials (BBM). Based on the summarized data from the literature a connection between the materialinduced tissue reactions and the consequences for the healing processes are presented with the aim for translation into their clinical application.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA