Naslov
Anisakis spp. Genomic Epidemiology-Scratching the Surface of an Emerging Zoonosis

Autori
Mladineo, Ivona ; Trumbić, Željka ; Bušelić, Ivana ; Hrabar, Jerko ; Vrbatović, Anamarija ; Nonković, Diana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Book of abstracts of 7th International Conference “Prevention of trichinosis, anisakiasis and other foodborne parasitoses” / Cencek, Tomasz - Puławy : Panstwovy Instytut Weterynaryny, 2018, 17-17

Skup
Parasitological Conference "Prevention of trichinosis, anisakiasis and other parasitic parasitoses"

Mjesto i datum
Rogowo, Poljska, 11.09.2018. - 13.09.2018

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Anisakis, epidemiology, experimental infection, RNA Seq, seroprevalence, risk assessement

Sažetak
Global migration, changes in dietary habits such as eating raw or undercooked food, higher demand and availability of exotic food as well as climate change have been listed as major reasons for a considerable increase in reported cases of foodborne parasitic zoonoses, leading to their recognition as an emerging public health problem. Therefore, prevention and protection against zoonotic parasites, especially in fishery products designated for human consumption, has recently become a priority. Consequently, health authorities and fishing industry have become aware of the significance of the nematodes of the genus Anisakis, affecting both human health and commercial value of fishery products. Although considered as one of the most significant emerging foodborne zoonosis, anisakiasis is still misdiagnosed and underreported in many Mediterranean countries. During a four-year research within the AnGEl project (Anisakis spp. Genomic Epidemiology) funded by the Croatian Science Foundation, we have assessed Anisakis nematodes using multidisciplinary approach, studying fish as paratenic, cetaceans as final and men as accidental hosts. The results of the project expanded our knowledge on: i) molecular geo-distribution of Anisakis spp. in the Adriatic fish inferred by a newly developed genome-derived small sequence repeats (SSR) panel, ii) histopathological effect of the nematode in the digestive tract of paratenic, final and model accidental host inferred by IHC and TEM, iii) nematode transcriptomic signature during migration through model host using RNAseq and microRNA profiling, iv) traits of the larval multixenobiotic resistance mechanisms that will help design more effective therapy, v) anti-Anisakis IgE seroprevalence in human population professionally related to fish processing industry. The most important results will be presented, aiming to trigger better conscience and take home message about this emerging and highly under- and miss-diagnosed zoonosis.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Javno zdravstvo i zdravstvena zaštita, Veterinarska medicina, Biotehnologija

POVEZANOST RADA