Naslov
ANTIMICROBIAL SUSCEPTIBILITY OF THE MOST COMMON PATHOGENS ISOLATED FROM URINARY TRACT INFECTIONS IN STROKE PATIENTS

Autori
Cviljević, Sabina ; Lovrić, Božica ; Petković, Dobrinka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstract book 2018 / - Pula, 2018, 74-75

Skup
58. Međunarodni neuropsihijatrijski kongres (MIND & BRAIN)

Mjesto i datum
Pula, Hrvatska, 25.05.2018. - 27.05.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Urinary tract infections ; stroke

Sažetak
Introduction/Objectives: Stroke is one of the leading causes of morbidity and mortality worldwide. It is often followed by complications, especially infections. Pneumonia and urinary tract infections (UTIs) are the most common post stroke infections that lead to poor clinical outcome. Patients with stroke are particularly vulnerable to UTIs due to increased risk from immunosuppression, bladder dysfunction, and increased Foley catheter use. Escherichia coli (E. coli) is the most common pathogen isolated from urinary cultures. Other Enterobacteriaceae are also common such as Klebsiella, Proteus, Pseudomonas. Clinicians often choose empirical antimicrobial therapy for urinary infections treatment. Inappropriate use of antimicrobials leads to the development of resistant microorganisms and failure of therapy. The aim of this study was to determine the prevalence and antimicrobial susceptibility of the most common microorganisms isolated from the urinary tract infections in stroke patients. Participants, Materials/Methods: In this retrospective study, we have selected 307 patients from the hospital information system who were treated in our Hospital for diagnosis according to the MKB diseases codes I60- I69, over a two year period. We have processed urine culture results taken after stroke. Identification and antimicrobial susceptibility of urinary pathogens were determined according to standard laboratory protocol. Culture samples were recorded as positive when uropathogens were detected at ≥10⁴ colony forming units (CFU)/ml for urine catheter samples regarding to midstream urine samples at ≥10⁵ CFU/ml. Results: In this study, we processed 110 (36 %) male and 197 (64 %) female patients. The median age was 78. Urinary catheters were placed in 138 patients (45 %). Out of the 307 urine samples submitted, 80 samples (26 %) were positive for bacterial growth. The most common isolate was E. coli (37.5 %). Antimicrobial susceptibility of E. coli was the highest to carbapenems (100 %), piperacillin-tazobactam (100 %), third and fourth generation cephalosporins (90 %). The resistance rates were the highest to ampicillin (53 %) and cotrimoxazol (33 %). Conclusions: Urinary tract infections remain a common occurrence in stroke patients. The overall prevalence of UTIs in our study was 26 %. These regional resistance data can help to clinicians to select appropriate empirical antimicrobial therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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