Naslov
Cimetna kiselina i njeni derivati
(Cinnamic acid and cinnamic acid derivatives)

Autori
Pavić, Kristina ; Zorc, Branka

Izvornik
Farmaceutski glasnik : glasilo Hrvatskog farmaceutskog društva (0014-8202) 74 (2018), 6; 415-428

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
cimetna kiselina ; biološko djelovanje ; lijekovi
(cinnamic acid ; biological activity ; drugs)

Sažetak
Cinnamic acid (3-phenylpropenoic or phenylacrylic acid) and its derivatives occur naturally in a number of plants. Th ey are precursors in the biosynthetic pathways of many alkaloids, aromatic amino acids, phenylpropanoids, styrenes, stilbenes, coumarins, lignins and fl avonoids, and are present in various essential oils, gums and balsams. Cinnamic acid derivatives are used in large quantities in the food, cosmetic and pharmaceutical industries. In addition, they possess a variety of pharmacological activities: antimicrobial, antitubercular, antioxidative, antimicrobial, antimalarial, antiviral, antidiabetic, hepatoprotective, antidepressant, anxiolytic, hypolipemic, anti-infl ammatory and cytostatic activities. Several drugs with cinnamic acid motifs are used in modern therapy (panobinostat, belinostat, cinanserin, tranilast, ozagrel and entacapone).

Izvorni jezik
Hrvatski

Znanstvena područja
Farmacija

POVEZANOST RADA