Naslov
A computational model of ureteral peristalsis and an investigation into ureteral reflux

Autori
Hosseini, G. ; Ji, C. ; Xu, D. ; Rezaienia, M. A. ; Avital, E. ; Munjiza, A. ; Williams, J. J. R. ; Green, J. S. A.

Izvornik
Biomedical Engineering Letters (2093-9868) 8 (2017), 1; 117-125

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
CFD Ureter Reflux PUJ VUJ VUR

Sažetak
The aim of this study is to create a computational model of the human ureteral system that accurately replicates the peristaltic movement of the ureter for a variety of physiological and pathological functions. The objectives of this research are met using our in-house fluid-structural dynamics code (CgLes–Y code). A realistic peristaltic motion of the ureter is modelled using a novel piecewise linear force model. The urodynamic responses are investigated under two conditions of a healthy and a depressed contraction force. A ureteral pressure during the contraction shows a very good agreement with corresponding clinical data. The results also show a dependency of the wall shear stresses on the contraction velocity and it confirms the presence of a high shear stress at the proximal part of the ureter. Additionally, it is shown that an inefficient lumen contraction can increase the possibility of a continuous reflux during the propagation of peristalsis

Izvorni jezik
Engleski

Znanstvena područja
Interdisciplinarne tehničke znanosti, Temeljne medicinske znanosti

POVEZANOST RADA