Naslov
Heart rate is associated with renal parameters in patients with type 1 diabetes and normal renal function

Autori
Bulum, Tomislav ; Prkačin, Ingrid ; Roso, Vinko ; Duvnjak, Lea

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Journal of Hypertension. 2018 ; 36(e-Suppl. 1) / - , 2018, 190-191

Skup
28th European Meeting on Hypertension

Mjesto i datum
Barcelona, Španjolska, 08.06.2018. - 11.06.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
heart rate ; albuminuria ; renal function

Sažetak
Study included 313 normoalbuminuric T1DM with estimated glomerular filtration rate (eGFR) > 60 mlmin-11.73m-2. Serum creatinine was significantly associated with BMI, HbA1c, HDL- cholesterol, SBP and HR, with HR showing the strongest correlation (r = −0.17, p = 0.002). eGFR was significantly associated with duration of diabetes, HbA1c, LDL cholesterol, and HDL cholesterol, with duration of diabetes showing the strongest correlation (r = −0.29, p < 0.001). UAE significantly correlated with duration of diabetes, HDL cholesterol, triglycerides, HR and DBP, with HR and DBP showing the strongest correlation (r = 0.21– 0.23, p < 0.001). Subjects in the 4th quartile of UAE had significantly higher HR rate compared to subjects in 1st, 2nd, and 3rd quartiles (70 ± 11 vs 74 ± 12 vs 74 ± 12 vs 79 ± 13 beats/min, p = 0.001). Subjects in the 4th quartile of serum creatinine had significantly lower HR compared to subjects in 1st, 2nd, and 3rd quartiles (77 ± 13 vs 75 ± 13 vs 73 ± 11 vs 71 ± 13 betas/min, p = 0.03). Results of our study suggest that interplay between HR and renal function parameters are present even in T1DM with normal renal function and that higher HR may be predictor for higher UAE in those subjects.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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