Pregled bibliografske jedinice broj: 938
Antioxidant-independent oxidation od low density lipoprotein
Antioxidant-independent oxidation od low density lipoprotein // Abstract Book of the 66th Congress of the European Atherosclerosis Society / Paoletti, R. (ur.).
Firenza : München: Fondazione Giovanni Lorenzini, 1966. (poster, nije recenziran, sažetak, znanstveni)
CROSBI ID: 938 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Antioxidant-independent oxidation od low density lipoprotein
Autori
Herak, Janko Nikola ; Krilov, Dubravka ; Ukrainczyk, Tatjana
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Abstract Book of the 66th Congress of the European Atherosclerosis Society
/ Paoletti, R. - Firenza : München : Fondazione Giovanni Lorenzini, 1966
Skup
66th Congress of the European Atherosclerosis Society
Mjesto i datum
Firenca, Italija, 13.07.1996. - 17.07.1996
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
Lipoproteins; Lipoprotein oxidation; LDL mild oxidation
Sažetak
Oxidized low density lipoprotein (LDL) has been postulated to play an important role in atherogenesis. From the in vitro studies the transition-metal ions in conjunction with preformed lipid peroxides seem to be crucial for the initiation of lipoprotein oxidation. Our experiments show that the LDL oxidation takes place also under highly unfavorable conditions for oxidation: LDL solution in the deionized water, with chelates present, in a closed system with limited access of oxygen. The dissolved oxygen is used up within hours without simultaneous loss of the lipid-soluble antioxidants, or production of the thiobarbituric-acid-reactive substances (TBARS). After depletion of oxygen, free radicals assocoated with the lipid domain are formed. These findings suggest an alternative mechanism of the LDL oxidation. LDL oxidized in this way may be termed to be mildly oxidized.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
