Naslov
Association of Circadian Rhythm with Myocardial Infarction

Autori
Škrlec, Ivana ; Milić, Jakov ; Heffer, Marija ; Steiner, Robert ; Peterlin, Borut ; Wagner, Jasenka

Izvornik
Acta clinica Croatica (0353-9466) 57 (2018), 3; 480-486

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Cardiovascular Diseases ; Circadian Rhythm ; Myocardial Infarction

Sažetak
Cardiovascular diseases are the world’s leading cause of death. Human physiological activities and state during illness are under the control of circadian rhythm. The aim of the study was to determine the potential association of chronotype and daytime sleepiness with susceptibility toward myocardial infarction (MI). We conducted a case-control study on 200 patients hospitalized due to MI and 200 healthy controls. Systematic information on the past and present medical history were obtained from all participants. Chronotype was assessed using the Morningness-Eveningness Questionnaire (MEQ), and daytime sleepiness was assessed by Epworth Sleepiness Scale (ESS). The mean age of the study population was 64±13 years, and 54.5% were male. There was no significant difference in MEQ (58.88±6.52 vs. 58.46±7.78, p=0.601) or ESS (5 (interquartile range, IQR 4-7.5) vs. 6 (IQR 3- 8), p=0.912) score between patients and controls. Nevertheless, we found statistically significant differences related to risk factors for cardiovascular diseases, such as hypertension, dyslipidemia, and diabetes mellitus. However, there was no association of MEQ and ESS score with myocardial infarction in the studied population.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA