Naslov
Impact of valsartan and combination of valsartan and hydrochlorothiazide on erectile disfunction in patients with mild to moderate hypertension

Autori
Salobir, Barbara ; Brguljan Hitij, Jana ; Dolenc, Petra ; Chazova, Irina ; Sirenko, Yuriy ; Vincelj, Josip ; Widimsky, Jiri ; Barbic Zagar, Breda ; Accetto, Rok

Izvornik
Journal of hypertension (0263-6352) 34e (2016), 2; E275-e275

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
Valsartan ; erectile disfunction ; arterial hypertension
(valsartan ; erectile disfunction ; arterial hypertension)

Sažetak
Erectile disfunction is recognised quality of life disorder frequently occuring in hypertensive patients. The aim of our study was to assess the effect of treatment with valsartan and valsartan- HCTZ on erectile function. We assessed erectile dysfunction in 98 patietnts, aged 40-79 years with mild to moderate hypertension, participating in international, multicentre, open labelled trial - VICTORY (sponsored by KRKA, d.d.) using the questionare IIEF-5, before and after 16 week of treatment with valsartan or valsartan-HCTZ. At the end of the trial, in 90.6% of patients, the goal blood pressure, according to 2013 ESH/ESC Guidelines for the management of arterial hypertension, was achieved. The slight statistically significant increase in men IIEF-5 score after 16 weeks treatment was observed in patients on monotherapy with valsartan and in patients on combination therapy. Treatment with valsartan as well as adding low dose HCTZ to valsartan did not lead to deterioration of erectile function in patients with mild to moderate hypertension.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA