Naslov
Omega-3 polyunsaturated fatty acids enriched hen eggs consumption enhances microvascular reactivity in young healthy individuals

Autori
Stupin, Ana ; Rašić, Lidija ; Matić, Anita ; Stupin, Marko ; Kralik, Zlata ; Kralik, Gordana ; Grčević, Manuela ; Drenjančević, Ines

Izvornik
Applied physiology nutrition and metabolism - physiologie appliquee nutrition et metabolisme (1715-5312) 43 (2018), 10; 988-995

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
omega-3 PUFAs ; vascular function ; microcirculation ; laser Doppler flowmetry ; serum lipid profile

Sažetak
Whilst the beneficial effect of omega-3 polyunsaturated fatty acids (PUFAs) supplementation on cardiovascular (CV) system is well supported in CV patients, the effect of consumption of omega-3 PUFAs enriched functional food in healthy individuals is still not fully elucidated. This study aimed to determine the effect of consumption of omega-3 PUFAs enriched hen eggs on microvascular reactivity (primary outcome), blood pressure (BP) and serum lipid profile in young healthy individuals. Control group (N=16) ate three ordinary hen eggs (277 mg omega-3 PUFAs/day), and OMEGA-3 group (N=20) ate three omega-3 PUFAs enriched eggs containing 259 mg of omega- 3 PUFAs/egg daily (ALA 167 mg/egg, EPA 7 mg/egg, DHA 84 mg/egg) for 3 weeks (777 mg omega-3 PUFAs/day). Post-occlusive reactive hyperemia (PORH) in skin microcirculation assessed by laser Doppler flowmetry, serum lipid profile, fasting blood glucose, high- sensitivity C- reactive protein (hsCRP) and arterial BP were measured in all subjects before and after the protocol. PORH was significantly enhanced, and triglycerides, hsCRP and BP were significantly decreased in OMEGA-3 group compared to baseline measurement, while there was no significant difference in Control group after the protocol compared to baseline. This is the first study to demonstrate that consumption of a mixture of omega-3 PUFAs (ALA+EPA+DHA), provided via enriched hen eggs, elicits changes in microvascular reactivity, BP and triglycerides level in healthy subjects that are associated with CV benefits, thus suggesting that daily consumption of omega-3 PUFAs enriched eggs in healthy individuals may potentially contribute to CV risk factors attenuation and disease prevention.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Poljoprivreda (agronomija), Biotehnologija

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