Naslov
Relapse of Pleomorphic Adenoma from Childhood to Adulthood: Case Report

Autori
Grabovac, Stjepan ; Grabovac, Đurđica ; Puharić, Zrinka ; Malčić Dalipi, Vesna

Izvornik
Acta clinica Croatica (0353-9466) 56 (2017); 812-816

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Adenoma, pleomorphic ; Submandibular gland ; Neoplasm recurrence, local

Sažetak
Pleomorphic adenoma is rarely seen in childhood. After detailed literature search, we did not come across a case of frequent relapse of this benign tumor from childhood to adulthood. Th e World Health Organization defi nes relapse of pleomorphic adenoma as a histologically benign tumor that can have local or distant metastasis. Th ere is one hypothesis how benign tumor can metastasize. According to this hypothesis, probably during the fi rst operative procedure the tissue around the tumor becomes permeable for tumor cells, which can lead to implantation of tumor cells into the surrounding tissue. In this case report, we present a case of a 30-year-old woman with pleomorphic adenoma of the submandibular gland, which relapsed three times. Th e patient was fi rst operated on in 1993, at the age of 7 years. Th e fi rst two relapses occurred in 1998 and 2001, at the age of 12 and 15, respectively. Th e last relapse occurred in 2015, at the age of 29 years. All relapses were localized in the submandibular region on the right side of the neck, where the primary tumor had been operated on.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA