Pregled bibliografske jedinice broj: 93241
Growth of Listeria monocytogenes in different organs of BALB/c mice after intragastric infection
Growth of Listeria monocytogenes in different organs of BALB/c mice after intragastric infection // Pover of microbes in industry and environment / Mrša, Vladimir; Hajsig, Danko (ur.).
Zagreb: Prehrambeno-biotehnološki fakultet Sveučilišta u Zagrebu, 2002. (poster, nije recenziran, sažetak, znanstveni)
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Naslov
Growth of Listeria monocytogenes in different organs of BALB/c mice after intragastric infection
Autori
Bubonja, Marina ; Dorić, Miljenko ; Abram, Maja
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Pover of microbes in industry and environment
/ Mrša, Vladimir; Hajsig, Danko - Zagreb : Prehrambeno-biotehnološki fakultet Sveučilišta u Zagrebu, 2002
Skup
Croatian, Hungarian and Slovenian Symposium on Industrial Microbiology and Microbial Ecology: Power of Microbes in Industry and Environment
Mjesto i datum
Opatija, Hrvatska, 07.06.2002. - 09.06.2002
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
Listeria monocytogenes; intragastric; mice
Sažetak
It is well established that ingestion of Listeria monocytogenes can cause serious human illness. Most cases occur in pregnant women or individuals with a predisposing disease or an impaired immune system. In non-pregnant adults, septicemia and meningitis/meningoencephalitis are the most common outcome of infection, although organ infections and mild gastroenteritis can also occur. Experimental listeriosis has yielded considerable insight into pathogenesis and host resistance mechanisms against this bacterium. We studied the clearance of L. monocytogenes from different organs of BALB/c mice following intragastric inoculation of bacteria. Our previous results have shown that a single high dose, applied intragastrically, caused severe systemic infection with a high mortality rate. If lower doses of Listeria were repeatedly applied by the same route of infection a prolonged survival of experimental animals was seen. However, the systemic infection was equally pronounced, as shown by high titar or bacteria and histological lesions found in the examined organs. In addition. L. monocytogenes was isolated from the brains of all infected mice. These data suggest two hypothesis for human infection. A single high dose or prolonged consumption of low doses of L. monocytogenes may result in clinically evident illness.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
