Pregled bibliografske jedinice broj: 930256
A young researcher’s guide to NME/Nm23/NDP Kinase
A young researcher’s guide to NME/Nm23/NDP Kinase // Periodicum biologorum, 120 (2018), 1; 3-9 doi:10.18054/pb.v120i1.6229 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 930256 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
A young researcher’s guide to NME/Nm23/NDP Kinase
Autori
Herak Bosnar, Maja ; Radić, Martina ; Ćetković, Helena
Izvornik
Periodicum biologorum (0031-5362) 120
(2018), 1;
3-9
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
Nm23 ; NME ; NDPK ; metastasis supressor
Sažetak
Nucleoside diphosphate kinases (NDPKs) catalyze the exchange of the terminal phosphate from trinucleotides to dinucleotides through a high- energy phosphohistidine intermedier. They are encoded by NME genes and have been found, with a few exceptions, in all living beings. Besides their well-known function as key regulators of the cellular nucleotide homeostasis, they have been appointed numerous additional biochemical and biological functions. The discovery of NME1/NDPK A as the first metastasis suppressor opened new avenues in cancer research. Although the precise role of NME genes/proteins in cancer dissemination is not yet revealed, it seems that further intensive research in this field may lead to new advances in cancer diagnosis and prognosis, as well as encourage new therapeutic strategies.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
HRZZ-IP-2016-06-4021 - Struktura, funkcija i evolucija proteina Nme6/Nm23-H6 (Nemo6) (Herak-Bosnar, Maja, HRZZ - 2016-06) ( CroRIS)
HRZZ-IP-2014-09-6400 - Istraživanje razvoja, diferencijacije i evolucije životinja kroz genomiku bazalnih metazoa (BAMGEN) (Vlahoviček, Kristian, HRZZ - 2014-09) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
