Pregled bibliografske jedinice broj: 918975
Control of Enantioselectivity in Rhodium(I) Catalysis by Planar Chiral Dibenzo[a, e]cyclooctatetraenes
Control of Enantioselectivity in Rhodium(I) Catalysis by Planar Chiral Dibenzo[a, e]cyclooctatetraenes // Chemistry : a European journal, 24 (2018), 10; 2344-2348 doi:10.1002/chem.201704816 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 918975 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Control of Enantioselectivity in Rhodium(I) Catalysis by Planar Chiral Dibenzo[a, e]cyclooctatetraenes
Autori
Melcher, Michaela-Christina ; Ivšić, Trpimir ; Olagnon, Charlotte ; Tenten, Christina ; Lützen, Arne ; Strand, Daniel
Izvornik
Chemistry : a European journal (0947-6539) 24
(2018), 10;
2344-2348
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
asymmetric catalysis ; cyclooctatetraenes ; fenestrenes ; planar chirality ; rhodium
Sažetak
Planar chiral 5, 11-disubstiuted dibenzo[a, e]cyclo- octatetraenes (dbCOTs) have been developed as the first useful chiral homologs to dbCOT-ligands for asymmetric applications. Methods enabling the preparation of such compounds on a gram-scale in enantiomerically pure form are described. Evaluated as ligands in rhodium(I)-catalyzed 1, 4- and 1, 2-arylation reactions, tertiary and quarternary stereogenic centers were formed with excellent yields and selectivities of up to > 99 % ee. A catalytic asymmetric synthesis of a key cyclization precursor to (À)-penifulvin A highlights the system in an applied context.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- Arts & Humanities Citation Index (A&HCI)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
