Naslov
Comminution kinetics of α and γ-glycine polymorphs in a planetary ball mill

Autori
Matijašić, Gordana ; Mandić, Vanda ; Žižek, Krunoslav ; Prlić Kardum, Jasna ; Hrkovac, Martina ; Mandić, Vilko

Izvornik
American Journal of Engineering, Technology and Society (2381-6171) 4 (2017), 5; 57-65

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Glycine, Crystal Size Distribution, Comminution Kinetics, Population Balance, Polymorph

Sažetak
Glycine is the important amino acid that functions as inhibitory neurotransmitter and therefore has been a topic of many researches. This work deals with modeling of the comminution process for glycine crystals. Three different glycine samples (two γ and one α form) were prepared by batch cooling crystallization and afterwards comminuted in a planetary ball mill. Comminution kinetics was investigated using the analytical solution of population balance. Crystal size distribution was expressed with Sauter's mean diameter and modeled using simple first-order breakage kinetic with a milling limit. Results showed the obtained models can be used to predict crystal size distribution during the comminution process. PXRD analysis showed there was no mechanically induced solid-state polymorphic phase transformation of glycine.

Izvorni jezik
Engleski

Znanstvena područja
Kemijsko inženjerstvo

POVEZANOST RADA