Naslov
Amyloid in Acquired Aponeurotic Ptosis

Autori
Kuzmanović, Biljana

Izvornik
Acta clinica Croatica. Supplement (0353-9474) 41 (2002), 4; 11-16

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Aponeurotic ptosis ; Amyloidosis ; Aponeurosis histopathology

Sažetak
ABSTRACT - PURPOSE: Histopathological and immunohistochemical evaluation of levator aponeurosis in patients with aponeurotic ptosis vs. control aponeurosis obtained from autopsies of cadavers without history of ptosis, especially in relation with presence of amyloid deposition. MATERIAL AND METHODS: Seven levator specimens were taken from 6 patients, undergoing anterior levator repair due to aponeurotic ptosis. The control group consisted of 12 levator aponeurosis specimens harvested from both lids of 6 cadavers, during autopsy. Congo red was used to detect amyloid and Orcein stain for elastic fibers. Immunohistochemistry was applied as a final marker for amyloid. RESULTS: In 2 out of 6 (33, 3%) aponeurotic patients we demonstrated amyloid. Orbital and systemic involvement was excluded. The levator aponeurosis was attenuated, stretched and grayish in all patients, but still attached to the tarsus. Collagen bundles were thinned with fatty and elastotic degeneration of different grade in all samples. Control group was negative for amyloid. CONCLUSION: We demonstrated amyloid in 33, 3% of patients with aponeurotic ptosis, without systemic amyloidosis, which may open a new perspective in aponeurotic ptosis etiology explanation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA