Naslov
Antibacterial and antifungal activity of extracts and quercetagetin derivate isolated from Centaurea rupestris L. (Asteraceae)

Autori
Rusak, Gordana ; Robinson, Neil ; Pepeljnjak, Stjepan

Izvornik
Acta Biologica Cracoviensia (Series Botanica) (0001-5296) 44 (2002); 169-174

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Centaurea rupestris L.; flavonoids; quercetagetin; antibacterial activity; antifungal activitiy

Sažetak
The antibacterial and antifungal activity of Centaurea rupestris L. ethanolic and etheric leaf and inflorescence extracts and of quercetagetin 3'-methyl ether 7-O-beta-D glucopyranoside isolated from inflorescences was investigated. Inflorescence extract in 45% ethanol showed significant antifungal activity against the dermatophytes Epidermophyton floccosum, Microsporium gypseum and Trichophyton mentagrophytes (fungicidal zones between 18 and 23 mm, minimum fungicidal concentration 5-7%). The same extract showed weak bactericidal acitvity against Bacillus anthracis (bactericidal zone 9 mm, minimun bactericidal concentration 90%). In contrast, leaf extract in 90% ethanol possessed significant bactericidal activity against streptococcus faecalis (bactericidal zone 23 mm, minimum bactericidal concentration 9%). The antimicrobial spectrum of quercetagetin was broad but weak for G- bacteria and moderate for dermatophytes. Namely, it showed antibacterial activity against Klebsiella pneumoniae, Escherichia coli, Salmonella java and Serratia sp. (bactericidal zones 10 mm, minimum bactericidal concentration 5-6 mg/ml). The fungicidal zones created by quercetagetin against the dermatophytes Epidermophyton floccosum, Trichophyton mentagraphytes and Microsporum gypseum ranged from 14 to 18 mm (minimun fungicidal concentrations 3 mg/ml).

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA