Pregled bibliografske jedinice broj: 90780
Meso- and racemic- DMSA as antidotes in heavy metal poisoning
Meso- and racemic- DMSA as antidotes in heavy metal poisoning // Proceedings of the Chemical and Biological Medical Treatment Symposium - CBMTS - Industry II / Bokan, Slavko ; Orehovec, Zvonko (ur.).
Zagreb : Aberdeen (MD), 2002. str. 91-95 (poster, međunarodna recenzija, cjeloviti rad (in extenso), pregledni)
CROSBI ID: 90780 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Meso- and racemic- DMSA as antidotes in heavy metal poisoning
Autori
Blanuša, Maja ; Piasek, Martina ; Kostial, Krista ; Jones, Mark M. ; Singh, Pramod K.
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, cjeloviti rad (in extenso), pregledni
Izvornik
Proceedings of the Chemical and Biological Medical Treatment Symposium - CBMTS - Industry II
/ Bokan, Slavko ; Orehovec, Zvonko - Zagreb : Aberdeen (MD), 2002, 91-95
Skup
The First World Congress on Chemical and Biological Terrorism
Mjesto i datum
Dubrovnik, Hrvatska, 21.04.2001. - 27.04.2001
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
lead; cadmium; mercury; meso- and racemic-1; 3-dimercaptosuccinic acid
Sažetak
The results of our investigations presented and reviewed in this paper have been obtained in experimental animal models in vivo and published earlier. Two chelating agents were compared for their mobilising potency of reducing lead, cadmium and mercury body retention. The results show that the racemic isoform of DMSA is more efficient in reducing the body burden and target organ retention of toxic metals than meso-DMSA. The efficiency of metal body burden reduction with rac-DMSA was ordered: mercury>lead>cadmium. These studies will be continued to assess whether rac-DMSA could be applied clinically.
Izvorni jezik
Engleski
Znanstvena područja
Javno zdravstvo i zdravstvena zaštita
POVEZANOST RADA
Projekti:
00220102
Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb
