Naslov
Antioxidant Phytochemicals at the Pharma-Nutrition Interface - Editorial

Autori
Azzini, Elena ; Giacometti, Jasminka ; Russo, Gian Luigi

Izvornik
Oxidative Medicine and Cellular Longevity (1942-0900) 2017 (2017); 6986143, 3

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, uvodnik, znanstveni

Ključne riječi
Phytochemicals, Pharma nutrition

Sažetak
Noncommunicable diseases (NCDs), including obesity, diabetes, cardiovascular diseases, and cancer, represent an emerging global health issue. Nutrition, as known, represents one of the most important aspects of health ; several researchers have shown that nutrition plays a crucial role in the prevention of food deficiencies, behavioural disorders, and chronic diseases. The last decades saw the proliferation of studies on the healthy benefits of specific classes of nutrients. Among these, phytochemicals took the lead for their capacity to act as antioxidants, a function which inspired the so-called “antioxidant hypothesis” or “free radical theory” for degenerative diseases originated back in the late 1980s–middle 1990s. After more than twenty years of intense researches, phytochemicals remain an éminence grise in the area of the natural remedies against degenerative diseases. In fact, if, from one side, their functional pleiotropy guarantees multiple therapeutic and preventive effects, their low bioavailability and high metabolic transformation represent an unsolved issue on the way to demonstrate a clear structure-function relationship in regulating cellular physiology. The aim of the present special issue was not to propose a solution for all the questions surrounding the mechanisms of action of phytochemicals but to bring the attention of the readers on specific themes with a selection of high quality research articles and reviews, hoping to stimulate their thinking. This special issue comprising nine papers is focused on various aspects of phytochemicals effects when administered as extracts in animal and cellular models. The articles have been selected on the basis of fundamental ideas/concepts rather than the thoroughness of techniques employed.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita, Nutricionizam

Napomena
This work has been supported by the University of Rijeka under the project number 13.11.1.2.02

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