Naslov
Seawater from dinoflagellate Ostreopsis ovata Fukuyo 1981 cultures causes increased permeability of nasal tissue

Autori
Millotti, Gioconda ; Laffleur, Flavia ; Smodlaka Tanković, Mirta ; Baričević, Ana ; Pfannkuchen, Martin

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
52nd European marine biology symposium / - Piran : National Institute of Biology, Marine Biology Station (NIB), 2017, 166-166

ISBN
978-961-93486-5-9

Skup
52nd European marine biology symposium

Mjesto i datum
Piran, Slovenija, 25.09.2017. - 29.09.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Ostreopsis ovata ; permeability ; nasal tissue

Sažetak
The species of the genus Ostreopsis produce a range of palytoxins and ovatoxins. Massive abundances are observed in shallow coastal areas, especially close to the shoreline in only a few meters of depth. Blooms with dramatic impacts on human health are so far mainly reported from the coasts around the Mediterranean. In the area around Genova, Italy, several hundred persons had to be hospitalized after exposure to aerosols during a bloom of Ostreopsis in summer 2005. Clinical symptoms range from rhinitis over asthma like symptoms, violent contractions of all muscle types, sperm immobility, to hemorrhagic and ultimately fatal effects. The rising interest in Ostreopsis, which is able to produce toxic aerosols along shorelines, resulted in searches for its distribution independent of reported impacts on human health. It was therefore the aim of this study to investigate the impact of the toxin on the modulation of the permeability across the porcine nasal mucosa, which is very similar to the human one. The study was performed using the Ussing chambers method. The results showed an increase in the permeability across the nasal mucosa, in comparison with only sea water, showing that this could be the cause for the respiratory problems induced by the toxin.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Farmacija

POVEZANOST RADA