Naslov
Central Preparation of Antineoplastic Drugs: Practice and Experiences

Autori
Gajski, Lidija ; Spasovska, Olivera ; Aleksić, D. ; Pavlica, Vesna

Izvornik
Libri oncologici : Croatian journal of oncology (0300-8142) 45 (2017), Supplement 1; 40-40

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
medical errors ; antineoplastics ; preparation

Sažetak
Medical errors related to antineoplastic drugs are subject to multilple researches, whereas in the Republic of Croatia, that is still a subject of discussion. Insufficient information which would serve as a basis for a conclusion about the extent medical error is present in Croatian hospital system. By supervising prescribed drugs, dosages, solutions, and correct preparation and instructions for accurate application, oncology pharmacists can to a great extent contribute to a safe application of drugs in hospitals, reducing, by doing so, the margin of medication error. Drugs that make part of the chemotherapy protocol of a patient, accompanied or not by biological therapy, get prepared in accordance with instructions from the Summaries of Product Characteristics (SPC). Due to individual differences between patients and the need to adjust these protocols, other referential data from literature are also used. Antineoplastic drugs are prepared in microbiologically validated space by manipulation in aseptic conditions. Sterile state of the prepared drug is of outstanding importance, because the immune system of oncology patients is often compromised due to side effects which are the consequence of the therapy itself. By organizing the entire procedure, from recieving and control of the request for chemotherapy, the pre-preparation procedure, the preparation, visual control of ready preparations, the packaging of chemotherapy and its application at wards, an entire system of multiple controls prior to application is established. In this way, we attempt to reduce the occurence of undesired events which could threaten the health of the patient and increase treatment costs. In everyday work the most used are the world and the national guidelines as well as QUAPOS - Quality Standard for the Oncology Pharmacy Service edited by ESOP ( European Society of Oncology Pharmacy).

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Farmacija

POVEZANOST RADA