Naslov
Level of arsenic in the urine of mountain ultra- marathon participants

Autori
Jablan, Jasna ; Stosnach, Hagen ; Ortner Hadžiabdić, Maja ; Inić, Suzana ; Domijan, Ana- Marija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Program and Book of abstract of the 17th International Conference on Total Reflection X- ray Fluorescence Analysis and Related Methods / Zacco, Annalisa - Brescia : Smart Solutions Srl, 2017, 82-82

ISBN
978-88-942891-0-7

Skup
17th International Conference on Total Reflection X-ray Fluorescence Analysis and Related Methods

Mjesto i datum
Brescia, Italija, 19.09.2017. - 22.09.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
arsenic, urine, TXRF, mountain ultra-marathon race

Sažetak
Arsenic is toxic metal recognised by International Agency for Research on Cancer (IARC) as carcinogenic to humans (Group 1). Human exposure to arsenic occurs by ingestion of contaminated food and water. Toxicokinetic studies indicate that arsenic after its absorption into blood is quickly transformed and eliminated from the body via urine. However, little is known on its accumulation and its toxicokinetics during and after physical activity. Therefore the aim of this study was to explore the level of arsenic in the urine of the participants of the mountain ultra-marathon race. Participants of the study were non-professional well-trained female and male individuals (n=21) who participated in a mountain ultra-marathon race at Medvednica, Zagreb, Croatia in the spring 2015. Urine samples were collected before, immediately after and 12 and 24 h after the race. Level of arsenic was determined by the use of the bench top TXRF (total reflection X-ray fluorescence) spectrometer “S2 Picofox” (Bruker Nano GmbH, Berlin, Germany). Before the race arsenic was detected in 81% of participants (17/21) and its mean concentration was 40.8 ± 88.8 μg/L. Immediately after the race arsenic was present in the urine of all participants and its mean concentration increased to 241.4 ± 539.7 μg/L (p = 0.016 ; Friedman test). However, 12 and 24 h after the race its concentration started to decrease. 12 h after the race arsenic was detected in 81% of participants and its mean concentration was 77.7 ± 69.5 μg/L, while 24 h after the race arsenic was again detected in 81% of participants with mean level 82.5 ± 93.2 μg/L. These results indicate that, although in low levels, arsenic is present in the urine of healthy individuals. However, the sport activity leads to its increase in the urine above acceptable level.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Javno zdravstvo i zdravstvena zaštita, Farmacija

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