Naslov
Cis- vs. trans- square-planar palladium(II) and platinum(II) complexes with triphenylphosphine amino acid bioconjugates

Autori
Kokan, Zoran ; Perić, Berislav ; Kovačević, Goran ; Brozovic, Anamaria ; Metzler-Nolte, Nils ; Kirin, Srećko I.

Izvornik
European journal of inorganic chemistry (1434-1948) 2017 (2017), 33; 3928-3937

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Palladium ; Platinum ; Phosphine ligands ; Amino acids ; Biological activity

Sažetak
Triphenylphosphine–amino acid bioconjugates Ph2P-pC6H4-Aa-OR [Lig ; Aa = glycine (1G), alanine (2A), valine (3V), isoleucine (4I), proline (5P), or phenylalanine (6F)] were synthesized and used as monodentate ligands for the preparation of twelve metal complexes, [MCl2(Lig)2] (M = PdII or PtII). All of the prepared compounds were characterized by spectroscopic methods, and the structures of ligand 1G and complexes 1GPd, 4IPd, and 6FPd were determined by X-ray single-crystal diffraction. The cis and trans configurations of the square-planar metal complexes were investigated by solution NMR spectroscopy and computational methods.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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