Naslov
Verification of tramadol abuse in patients on methadone substitutiontherapy

Autori
Horvat, Vesna ; Mandić, Sanja ; Mandić, Dario ; Bojanić, Ksenija ; Majetić-Cetina, Neda

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Toxicology Letters / - , 2006

Skup
EUROTOX 2006/6 CTDC Congress

Mjesto i datum
Cavtat, Hrvatska, 20.09.2006. - 24.09.2006

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
verification, tramadol, methadon

Sažetak
Methadone is a syntetic opioid, often used in the treatment of narcotic addiction. The oral use of methadone can suppres withdrawl symptoms, but in contrast to heroin, does not give any euphoric effect. However, this sensation can be induced by combinationwith alcohol, benzodiazepines, tramadol, etc. Therefore, regular urine testing should be carried out. We analyzed urines of 25 patients on methadone therapy with 3 methods: enzyme multipled immunoassay(EMIT), thin layer chromatography (TLC) and gas chromatography mass spectrometry (GC-MS). we assessed the efficacy of these methods in verification of tramadole abuse in patients on methadone substitution therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA